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MedKoo Cat#: 528033 | Name: Heliantriol B2

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Heliantriol B2 Antineoplastic Agents, Phytogenic; from Chuquiraga erinacea.

Chemical Structure

Heliantriol B2
Heliantriol B2
CAS#61229-18-3

Theoretical Analysis

MedKoo Cat#: 528033

Name: Heliantriol B2

CAS#: 61229-18-3

Chemical Formula: C30H50O3

Exact Mass: 458.3760

Molecular Weight: 458.73

Elemental Analysis: C, 78.55; H, 10.99; O, 10.46

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Heliantriol B2
IUPAC/Chemical Name
Lup-20(29)-ene-3,16,28-triol
InChi Key
TWKNDDJHVQUEJF-FQJNEUTDSA-N
InChi Code
InChI=1S/C30H50O3/c1-18(2)19-10-15-30(17-31)24(33)16-29(7)20(25(19)30)8-9-22-27(5)13-12-23(32)26(3,4)21(27)11-14-28(22,29)6/h19-25,31-33H,1,8-17H2,2-7H3/t19-,20+,21-,22+,23?,24?,25+,27-,28+,29+,30-/m0/s1
SMILES Code
CC1(C)C(O)CC[C@]2(C)[C@@]3([H])CC[C@]4([H])[C@@]5([H])[C@H](C(C)=C)CC[C@@](CO)5C(O)C[C@](C)4[C@@](C)3CC[C@@]12[H]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 458.73 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Gurovic MS, Lanza AM, Adánez Mdel C, Omaña MC, Gómez IG, Murray AP, López PS. Cytotoxic effects induced by combination of heliantriol B2 and dequalinium against human leukemic cell lines. Phytother Res. 2011 Apr;25(4):603-10. doi: 10.1002/ptr.3310. Epub 2010 Oct 26. PubMed PMID: 20981868. 2: Gurovic MS, Castro MJ, Richmond V, Faraoni MB, Maier MS, Murray AP. Triterpenoids with acetylcholinesterase inhibition from Chuquiraga erinacea D. Don. subsp. erinacea (Asteraceae). Planta Med. 2010 Apr;76(6):607-10. doi: 10.1055/s-0029-1240582. Epub 2009 Nov 16. PubMed PMID: 19918718. 3: Ukiya M, Akihisa T, Tokuda H, Suzuki H, Mukainaka T, Ichiishi E, Yasukawa K, Kasahara Y, Nishino H. Constituents of Compositae plants III. Anti-tumor promoting effects and cytotoxic activity against human cancer cell lines of triterpene diols and triols from edible chrysanthemum flowers. Cancer Lett. 2002 Mar 8;177(1):7-12. PubMed PMID: 11809525. 4: Yasukawa K, Akihisa T, Oinuma H, Kasahara Y, Kimura Y, Yamanouchi S, Kumaki K, Tamura T, Takido M. Inhibitory effect of Di- and trihydroxy triterpenes from the flowers of compositae on 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice. Biol Pharm Bull. 1996 Oct;19(10):1329-31. PubMed PMID: 8913506.