Decanoyl acetaldehyde | CAS# 56505-80-7

MedKoo Cat#: 581957 | Name: Decanoyl acetaldehyde

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Decanoyl acetaldehyde is a natural product, which is the main antibacterial component in the essential oil from Hottuynia cordata Thunb. Houttuyninum (decanoyl acetaldehyde; HOU) showed a strong suppressive effect on the mouse's ear edema induced by croton oil and on the rat's hid paw edema induced by carrageenin. HOU also inhibited vascular permeability induced by acetic acid in mice. In addition, a significant analgesic effect of HOU was observed on inflammatory pain caused by acetic acid, formaldehyde and heat stimulus.

Chemical Structure

Decanoyl acetaldehyde

CAS#56505-80-7

Theoretical Analysis

MedKoo Cat#: 581957

Name: Decanoyl acetaldehyde

CAS#: 56505-80-7

Chemical Formula: C12H22O2

Exact Mass: 198.1600

Molecular Weight: 198.31

Elemental Analysis: C, 72.68; H, 11.18; O, 16.14

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

56505-80-7

Synonym

3-Oxododecanal; Decanoyl acetaldehyde; Houttuynin; Houttuynine;

IUPAC/Chemical Name

3-oxododecanal

InChi Key

QBDCOUHKEVYWLO-UHFFFAOYSA-N

InChi Code

InChI=1S/C12H22O2/c1-2-3-4-5-6-7-8-9-12(14)10-11-13/h11H,2-10H2,1H3

SMILES Code

O=C(CC=O)CCCCCCCCC

Appearance

Liquid

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Houttuynia cordata Thunb. (H. cordata) is an anti-inflammatory herbal drug that is clin. used in Asia. The essential oil obtained from H. cordata is known to contain 2-undecanone (2-Me nonyl ketone). In addition, sodium houttuyfonate is a compound that can be derived from H. cordata and has important clin. uses as an anti-inflammatory agent. Sodium houttuyfonate can be converted to decanoyl acetaldehyde (houttuynin) and then to 2-undecanone.

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 198.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Li JJ, Chen GD, Fan HX, Hu D, Zhou ZQ, Lan KH, Zhang HP, Maeda H, Yao XS, Gao H. Houttuynoid M, an Anti-HSV Active Houttuynoid from Houttuynia cordata Featuring a Bis-houttuynin Chain Tethered to a Flavonoid Core. J Nat Prod. 2017 Nov 22;80(11):3010-3013. doi: 10.1021/acs.jnatprod.7b00620. Epub 2017 Nov 3. PubMed PMID: 29099182. 2: Chen J, Wang W, Shi C, Fang J. A comparative study of sodium houttuyfonate and 2-undecanone for their in vitro and in vivo anti-inflammatory activities and stabilities. Int J Mol Sci. 2014 Dec 11;15(12):22978-94. doi: 10.3390/ijms151222978. PubMed PMID: 25514406; PubMed Central PMCID: PMC4284749. 3: Gao Y, Gao JP, Chen CX, Wang HL, Guo J, Wu R. Beneficial effects of houttuynin on ventricular remodeling induced by coronary artery ligation in rats. Eur J Pharmacol. 2014 Oct 5;740:200-8. doi: 10.1016/j.ejphar.2014.07.015. Epub 2014 Jul 18. PubMed PMID: 25041841. 4: Chen SD, Li T, Gao H, Zhu QC, Lu CJ, Wu HL, Peng T, Yao XS. Anti HSV-1 flavonoid derivatives tethered with houttuynin from Houttuynia cordata. Planta Med. 2013 Dec;79(18):1742-8. doi: 10.1055/s-0033-1351051. Epub 2013 Nov 28. PubMed PMID: 24288290. 5: Deng Z, Zhong D, Chen X. Identification of modification sites on human serum albumin and human hemoglobin adducts with houttuynin using liquid chromatography coupled with mass spectrometry. Biomed Chromatogr. 2012 Nov;26(11):1377-85. doi: 10.1002/bmc.2708. Epub 2012 Feb 15. PubMed PMID: 22334394. 6: Qiu Y, He FY, Gong LM, Huang S, Zou H, Chen F, Luo JY. [In vivo studies on metabolic network compatibility of herba houttuyniae injection and sodium neohouttuynin injection in rats]. Zhong Yao Cai. 2010 Sep;33(9):1428-33. Chinese. PubMed PMID: 21243773. 7: Wang F, Ouyang P, Zuo Q, Peng WL, Zhang JX, Lai WY, Xu DL. [Effects of a new houttuyfonate derivative on proliferation of NIH3T3 cell and expression of syndecan-4 induced by tumor necrosis factor alpha]. Zhong Yao Cai. 2010 Jan;33(1):92-6. Chinese. PubMed PMID: 20518314. 8: Duan X, Zhong D, Chen X. Derivatization of beta-dicarbonyl compound with 2,4-dinitrophenylhydrazine to enhance mass spectrometric detection: application in quantitative analysis of houttuynin in human plasma. J Mass Spectrom. 2008 Jun;43(6):814-24. doi: 10.1002/jms.1382. PubMed PMID: 18286671. 9: Meng J, Dong XP, Zhou YS, Jiang ZH, Leung KS, Zhao ZZ. [Orthogonal experiment using SFE-CO2 in extraction of essential oil from fresh Houttuynia cordata and analysis of essential oil by GC-MS]. Zhongguo Zhong Yao Za Zhi. 2007 Feb;32(3):215-7. Chinese. PubMed PMID: 17432141. 10: Yang B, Wang RJ, Wang QP, Lu DM, Li H, Xiao YQ, Wang YY. [Studies on GC fingerprint of volatile oil of Houttuynia cordata]. Zhongguo Zhong Yao Za Zhi. 2006 Dec;31(24):2055-7. Chinese. PubMed PMID: 17357555. 11: Zhao ZZ, Jiang XJ, Wang L, Wei Z. [Studies on antimicrobial and antiviral compounds--synthesis of derivatives of decanoyl acetaldehyde (author's transl)]. Yao Xue Xue Bao. 1979 Jul;14(7):428-33. Chinese. PubMed PMID: 532640.