S 30972-1 | CAS#209617-63-0 | inhibitor

MedKoo Cat#: 585119 | Name: S 30972-1

Description:

WARNING: This product is for research use only, not for human or veterinary use.

S 30972-1 is a S16020-2 derivative that is more efficient in vivo than S16020-2, a feature that may relate to the fact that S30972-1 is less toxic than S16020-2.

Chemical Structure

S 30972-1

CAS#209617-63-0

Theoretical Analysis

MedKoo Cat#: 585119

Name: S 30972-1

CAS#: 209617-63-0

Chemical Formula: C27H32Cl2N4O5

Exact Mass: 562.1750

Molecular Weight: 563.48

Elemental Analysis: C, 57.55; H, 5.72; Cl, 12.58; N, 9.94; O, 14.20

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

S 30972-1; S30972-1; S-30972-1

IUPAC/Chemical Name

Pentanedioic acid, mono(1-(((2-(dimethylamino)ethyl)amino)carbonyl)-5,6-dimethyl-6H-pyrido(4,3-b)carbazol-9-yl) ester, dihydrochloride

InChi Key

NSBSOMWCNYNCBD-UHFFFAOYSA-N

InChi Code

InChI=1S/C27H30N4O5.2ClH/c1-16-18-10-11-28-25(27(35)29-12-13-30(2)3)20(18)15-21-19-14-17(8-9-22(19)31(4)26(16)21)36-24(34)7-5-6-23(32)33;;/h8-11,14-15H,5-7,12-13H2,1-4H3,(H,29,35)(H,32,33);2*1H

SMILES Code

O=C(OC1=CC2=C(N(C)C3=C2C=C(C(C(NCCN(C)C)=O)=NC=C4)C4=C3C)C=C1)CCCC(O)=O.[H]Cl.[H]Cl

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 563.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Kraus-Berthier L, Guilbaud N, Léonce S, Parker T, Genissel P, Guillonneau C, Goldstein S, Atassi G, Pierré A. Comparison of the pharmacological profile of an olivacine derivative and a potential prodrug. Cancer Chemother Pharmacol. 2002 Aug;50(2):95-103. Epub 2002 Jun 25. PubMed PMID: 12172972. 2: Malonne H, Farinelle S, Decaestecker C, Gordower L, Fontaine J, Chaminade F, Saucier JM, Atassi G, Kiss R. In vitro and in vivo pharmacological characterizations of the antitumor properties of two new olivacine derivatives, S16020-2 and S30972-1. Clin Cancer Res. 2000 Sep;6(9):3774-82. PubMed PMID: 10999772.