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MedKoo Cat#: 573943 | Name: Iodipamide meglumine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Iodipamide meglumine is a molecule used as a contrast medium. When administered in vivo, iodipamide is removed from the liver and secreted into the biliary tract. Like other organic iodine compounds, this agent blocks x-rays and appears opaque on x-ray film; thereby it enhances the visibility of the bile ducts and gallbladder during cholangiography and cholecystography procedures.

Chemical Structure

Iodipamide meglumine
Iodipamide meglumine
CAS#3521-84-4 (meglumine)

Theoretical Analysis

MedKoo Cat#: 573943

Name: Iodipamide meglumine

CAS#: 3521-84-4 (meglumine)

Chemical Formula: C34H48I6N4O16

Exact Mass: 1529.7333

Molecular Weight: 1530.19

Elemental Analysis: C, 26.69; H, 3.16; I, 49.76; N, 3.66; O, 16.73

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
606-17-7 (free base) 3521-84-4 (meglumine) 2618-26-0 (sodium)
Synonym
Adipiodone meglumine, Cholografin Meglumine, Iodipamide meglumine, Iodipamide methylglucamine salt, Meglumine iodipamide
IUPAC/Chemical Name
Benzoic acid, 3,3'-((1,6-dioxo-1,6-hexanediyl)diimino)bis(2,4,6-triiodo-, compd. with 1-deoxy-1-(methylamino)-D-glucitol (1:2)
InChi Key
DGIAUNUPXILTJW-VRWDCWMNSA-N
InChi Code
1S/C20H14I6N2O6.2C7H17NO5/c21-7-5-9(23)17(15(25)13(7)19(31)32)27-11(29)3-1-2-4-12(30)28-18-10(24)6-8(22)14(16(18)26)20(33)34;2*1-8-2-4(10)6(12)7(13)5(11)3-9/h5-6H,1-4H2,(H,27,29)(H,28,30)(H,31,32)(H,33,34);2*4-13H,2-3H2,1H3/t;2*4-,5+,6+,7+/m.00/s1
SMILES Code
CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC(=O)c1c(I)cc(I)c(NC(=O)CCCCC(=O)Nc2c(I)cc(I)c(C(=O)O)c2I)c1I
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 1,530.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Huang H, Zeng JP, Long Y. [Hyponatremia induced by iodipamide: three cases report]. Zhonghua Xin Xue Guan Bing Za Zhi. 2009 Jul;37(7):621. Chinese. PubMed PMID: 19961734. 2: Lee FT Jr, Sproat IA, Rappe AH, Violante MR, Bronson JP. Liver enhancement techniques in computed tomography. A comparison of intravenous bolus, computed tomographic portography, and iodipamide ethyl ester particle injections in a canine model. Invest Radiol. 1994 Jun;29 Suppl 2:S289-92. PubMed PMID: 7928259. 3: Yao SZ, Liu DZ, Nie LH. Potentiometric determination of iodipamide using an iodipamide ion-selective electrode. J Pharm Biomed Anal. 1990;8(4):373-7. PubMed PMID: 2100212. 4: Lauteala L, Kormano M, Violante MR. Accumulation and elimination of particulate iodipamide ethyl ester in the lungs and kidneys of the rat. A morphological study. APMIS. 1988 Jul;96(7):660-6. PubMed PMID: 3408591. 5: Sands MS, Violante MR, Gadeholt G. Computed tomographic enhancement of liver and spleen in the dog with iodipamide ethyl ester particulate suspensions. Invest Radiol. 1987 May;22(5):408-16. PubMed PMID: 3597009.