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MedKoo Cat#: 573907 | Name: Aminopotentidine ethanedioate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Aminopotentidine is a benzamide obtained by formal condensation of the carboxy group of 4-aminobenzoic acid with the primary amino group of 1-(2-aminoethyl)-2-cyano-3-{3-[3-(piperidin-1-ylmethyl)phenoxy]propyl}guanidine. It has a role as a H2-receptor antagonist. It is a member of guanidines, a member of benzamides, a substituted aniline, a nitrile, an aromatic ether and a member of piperidines.

Chemical Structure

Aminopotentidine ethanedioate
Aminopotentidine ethanedioate
CAS#140873-27-4 (ethanedioate)

Theoretical Analysis

MedKoo Cat#: 573907

Name: Aminopotentidine ethanedioate

CAS#: 140873-27-4 (ethanedioate)

Chemical Formula: C28H37N7O6

Exact Mass: 0.0000

Molecular Weight: 567.65

Elemental Analysis: C, 59.25; H, 6.57; N, 17.27; O, 16.91

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
140873-27-4 (ethanedioate) 140873-26-3 (free base)
Synonym
Aminopotentidine ethanedioate
IUPAC/Chemical Name
Benzamide, 4-amino-N-(2-(((cyanoamino)((3-(3-(1-piperidinylmethyl)phenoxy)propyl)amino)methylene)amino)ethyl)-, ethanedioate (1:1)
InChi Key
GQKBDAXMEZIMRZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C26H35N7O2.C2H2O4/c27-20-32-26(31-14-13-29-25(34)22-8-10-23(28)11-9-22)30-12-5-17-35-24-7-4-6-21(18-24)19-33-15-2-1-3-16-33;3-1(4)2(5)6/h4,6-11,18H,1-3,5,12-17,19,28H2,(H,29,34)(H2,30,31,32);(H,3,4)(H,5,6)
SMILES Code
O=C(NCC/N=C(NC#N)/NCCCOC1=CC=CC(CN2CCCCC2)=C1)C3=CC=C(N)C=C3.O=C(O)C(O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 567.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Petrache G, Pavelescu MD. The pharmacological activity of some new fluorescent small molecule histamine H2 receptor (H2-R) ligands, derived from aminopotentidine and squaramide, in the GTPase assay. Rev Med Chir Soc Med Nat Iasi. 2010 Jan-Mar;114(1):255-9. PubMed PMID: 20509312. 2: Zawilska JB, Woldan-Tambor A, Nowak JZ. Histamine H(2) -like receptors in chick cerebral cortex: effects on cyclic AMP synthesis and characterization by [(3) H]tiotidine binding. J Neurochem. 2002 Jun;81(5):935-46. PubMed PMID: 12065605.