Fosdenopterin | CAS# 150829-29-1 (free base) | Molybdenum Cofactor Deficiency

MedKoo Cat#: 558738 | Name: Fosdenopterin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Fosdenopterin, also known as ALXN 1101 and WHO 11150, is a drug for molybdenum cofactor deficiency. It was approved in 2/26/2021 for treatment of patients with the rare genetic disease molybdenum cofactor deficiency Type A

Chemical Structure

Fosdenopterin

CAS#150829-29-1 (free base)

Theoretical Analysis

MedKoo Cat#: 558738

Name: Fosdenopterin

CAS#: 150829-29-1 (free base)

Chemical Formula: C10H14N5O8P

Exact Mass: 363.0580

Molecular Weight: 363.22

Elemental Analysis: C, 33.07; H, 3.89; N, 19.28; O, 35.24; P, 8.53

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

2301083-34-9 (HBr) 150829-29-1 (free base)

Synonym

Fosdenopterin; ALXN1101; ALXN-1101; ALXN 1101; WHO 11150; WHO-11150; WHO11150; Nulibry;

IUPAC/Chemical Name

8-amino-2,12,12-trihydroxy-4a,5a,6,7,11,11a,12,12a-octahydro-[1,3,2]dioxaphosphinino[4',5':5,6]pyrano[3,2-g]pteridin-10(4H)-one 2-oxide

InChi Key

CZAKJJUNKNPTTO-UHFFFAOYSA-N

InChi Code

InChI=1S/C10H14N5O8P/c11-9-14-6-3(7(16)15-9)12-4-8(13-6)22-2-1-21-24(19,20)23-5(2)10(4,17)18/h2,4-5,8,12,17-18H,1H2,(H,19,20)(H4,11,13,14,15,16)

SMILES Code

O=C1C2=C(NC(OC(COP(O3)(O)=O)C3C4(O)O)C4N2)NC(N)=N1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

	Solvent	mg/mL	mM
Solubility
	Soluble in DMSO	0.0	100.00

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 363.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.