Synonym
Aminocarnitine, Amino-carnitine, Emeriamine
IUPAC/Chemical Name
1-Propanaminium, 2-amino-3-carboxy-N,N,N-trimethyl-, hydroxide, inner salt, (R)-
InChi Key
DAWBGYHPBBDHMQ-ZCFIWIBFSA-N
InChi Code
1S/C7H16N2O2/c1-9(2,3)5-6(8)4-7(10)11/h6H,4-5,8H2,1-3H3/t6-/m1/s1
SMILES Code
C([C@@H](CC(=O)[O-])N)[N+](C)(C)C
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
160.22
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Tassoni E, Conti R, Gallo G, Vincenti S, Dell'Uomo N, Mastrofrancesco L, Ricciolini R, Cabri W, Carminati P, Giannessi F. Aminocarnitine ureidic derivatives as inhibitors of carnitine palmitoyltransferase I. ChemMedChem. 2010 May 3;5(5):666-9. doi: 10.1002/cmdc.200900535. PubMed PMID: 20232438.
2: Chegary M, Te Brinke H, Doolaard M, Ijlst L, Wijburg FA, Wanders RJ, Houten SM. Characterization of L-aminocarnitine, an inhibitor of fatty acid oxidation. Mol Genet Metab. 2008 Apr;93(4):403-10. Epub 2008 Feb 20. PubMed PMID: 18077198.
3: Chiodi P, Maccari F, Ramacci MT. Tissue lipid accumulation by L-aminocarnitine, an inhibitor of carnitine-palmitoyltransferase-2. Studies in intact rats and isolated mitochondria. Biochim Biophys Acta. 1992 Jul 9;1127(1):81-6. PubMed PMID: 1627637.
