MedKoo Cat#: 573854 | Name: Ipidacrine hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ipidacrine hydrochloride is the HCl salt of Ipidacrine --- a reversible acetylcholinesterase inhibitor used in memory disorders. Ipidacrine directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels. Ipidacrine enhances not only choline, but also adrenaline, serotonin, histamine, and oxytocin effects on smooth muscle.

Chemical Structure

Ipidacrine hydrochloride
Ipidacrine hydrochloride
CAS#90043-86-0

Theoretical Analysis

MedKoo Cat#: 573854

Name: Ipidacrine hydrochloride

CAS#: 90043-86-0

Chemical Formula:

Exact Mass:

Molecular Weight:

Elemental Analysis:

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Amiridin HCl, Amiridin hydrochloride, Amiridine hydrochloride, Amiridine HCl, Ipidacrine hydrochloride, Ipidacrine HCl
IUPAC/Chemical Name
1H-Cyclopenta(b)quinoline, 2,3,5,6,7,8-hexahydro-9-amino-, monohydrochloride
InChi Key
FERZJAONQGPFCU-UHFFFAOYSA-N
InChi Code
1S/C12H16N2.ClH/c13-12-8-4-1-2-6-10(8)14-11-7-3-5-9(11)12;/h1-7H2,(H2,13,14);1H
SMILES Code
C1CCc2c(c(c3c(n2)CCC3)N)C1.Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 0.00 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Chernus VP, Vanchakova NP, Sivkova SK, Sivkov AS, Gorenkov RV. Ipidacrine in combination therapy regimens of functional constipation. Ter Arkh. 2018 Dec 30;90(12):48-55. doi: 10.26442/00403660.2018.12.000008. PubMed PMID: 30701833. 2: Ogura H, Kosasa T, Kuriya Y, Yamanishi Y. Comparison of inhibitory activities of donepezil and other cholinesterase inhibitors on acetylcholinesterase and butyrylcholinesterase in vitro. Methods Find Exp Clin Pharmacol. 2000 Oct;22(8):609-13. PubMed PMID: 11256231. 3: Onodera K, Kojima J, Wachi M. Ipidacrine (NIK-247), a novel antidementia, rapidly enters the brain and improves scopolamine-induced amnesia in rats during the Morris water maze task. Nihon Shinkei Seishin Yakurigaku Zasshi. 1998 Apr;18(2):33-7. PubMed PMID: 9656230.