MedKoo Cat#: 540042 | Name: Berteroin
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Berteroin is an erucin homolog and potential antioxidant. It is present in cruciferous vegetables, including Chinese cabbage, rucola salad leaves, and mustard oil. It decreases expression of androgen receptors in prostate cancer cells. It also decreases the release of pro-inflammatory cytokines in LPS-stimulated macrophages.

Chemical Structure

Berteroin
Berteroin
CAS#4430-42-6

Theoretical Analysis

MedKoo Cat#: 540042

Name: Berteroin

CAS#: 4430-42-6

Chemical Formula: C7H13NS2

Exact Mass: 175.0489

Molecular Weight: 175.30

Elemental Analysis: C, 47.96; H, 7.47; N, 7.99; S, 36.58

Price and Availability

Size Price Availability Quantity
10mg USD 300.00 Ready to ship
25mg USD 550.00 2 Weeks
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Synonym
Berteroin; KB-47947; LP-088984; OR-009512; KB47947; LP088984; OR009512; KB 47947; LP 088984; OR 009512
IUPAC/Chemical Name
(5-isothiocyanatopentyl)(methyl)sulfane
InChi Key
HBVIMVJTUQNSEP-UHFFFAOYSA-N
InChi Code
InChI=1S/C7H13NS2/c1-10-6-4-2-3-5-8-7-9/h2-6H2,1H3
SMILES Code
CSCCCCCN=C=S
Appearance
A solution in ethanol
Purity
>95% (or refer to the Certificate of Analysis), supplied as 10 mg/mL in ethanol solution
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Certificate of Analysis
Safety Data Sheet (SDS)

Preparing Stock Solutions

The following data is based on the product molecular weight 175.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kim YJ, Park SY, Lee JH. Berteroin ameliorates lipid accumulation through AMPK-mediated regulation of hepatic lipid metabolism and inhibition of adipocyte differentiation. Life Sci. 2021 Oct 1;282:119668. doi: 10.1016/j.lfs.2021.119668. Epub 2021 Jun 1. PMID: 34087283. 2: Jung YJ, Jung JI, Cho HJ, Choi MS, Sung MK, Yu R, Kang YH, Park JH. Berteroin present in cruciferous vegetables exerts potent anti-inflammatory properties in murine macrophages and mouse skin. Int J Mol Sci. 2014 Nov 11;15(11):20686-705. doi: 10.3390/ijms151120686. PMID: 25393510; PMCID: PMC4264190. 3: Fahey JW, Stephenson KK, Wade KL, Talalay P. Urease from Helicobacter pylori is inactivated by sulforaphane and other isothiocyanates. Biochem Biophys Res Commun. 2013 May 24;435(1):1-7. doi: 10.1016/j.bbrc.2013.03.126. Epub 2013 Apr 11. PMID: 23583386; PMCID: PMC4618678. 4: Kim MJ, Kim SH, Lim SJ. Comparison of the apoptosis-inducing capability of sulforaphane analogues in human colon cancer cells. Anticancer Res. 2010 Sep;30(9):3611-9. PMID: 20944144. 5: Kim SH, Singh SV. D,L-Sulforaphane causes transcriptional repression of androgen receptor in human prostate cancer cells. Mol Cancer Ther. 2009 Jul;8(7):1946-54. doi: 10.1158/1535-7163.MCT-09-0104. Epub 2009 Jul 7. PMID: 19584240; PMCID: PMC2779717.