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MedKoo Cat#: 573847 | Name: Amifloxacin mesylate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Amifloxacin mesylate is the mesylate salt of Amifloxacin --- a fluoroquinolone antibiotic with similar activity to ciprofloxacin.

Chemical Structure

Amifloxacin mesylate
Amifloxacin mesylate
CAS#88036-80-0 (mesylate)

Theoretical Analysis

MedKoo Cat#: 573847

Name: Amifloxacin mesylate

CAS#: 88036-80-0 (mesylate)

Chemical Formula: C17H23FN4O6S

Exact Mass: 430.1322

Molecular Weight: 430.45

Elemental Analysis: C, 47.44; H, 5.39; F, 4.41; N, 13.02; O, 22.30; S, 7.45

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
88036-80-0 (mesylate) 86393-37-5 (free base)
Synonym
Amifloxacin mesylate; Win 49,375-3; Win-49,375-3; Win49,375-3; Win 49375-3;
IUPAC/Chemical Name
6-Fluoro-1,4-dihydro-1-(methylamino)-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid monomethanesulfonate
InChi Key
IKMAVYOHGHYOIZ-UHFFFAOYSA-N
InChi Code
1S/C16H19FN4O3.CH4O3S/c1-18-21-9-11(16(23)24)15(22)10-7-12(17)14(8-13(10)21)20-5-3-19(2)4-6-20;1-5(2,3)4/h7-9,18H,3-6H2,1-2H3,(H,23,24);1H3,(H,2,3,4)
SMILES Code
CNn1cc(c(=O)c2c1cc(c(c2)F)N3CCN(CC3)C)C(=O)O.CS(=O)(=O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 430.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Venezia RA, Prymas LA, Shayegani A, Yocum DM. In vitro activities of amifloxacin and two of its metabolites. Antimicrob Agents Chemother. 1989 May;33(5):762-6. PubMed PMID: 2751287; PubMed Central PMCID: PMC172529. 2: Iravani A, Welty GS, Newton BR, Richard GA. Effects of changes in pH, medium, and inoculum size on the in vitro activity of amifloxacin against urinary isolates of Staphylococcus saprophyticus and Escherichia coli. Antimicrob Agents Chemother. 1985 Apr;27(4):449-51. PubMed PMID: 3890724; PubMed Central PMCID: PMC180072.