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MedKoo Cat#: 573846 | Name: Amifloxacin
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Amifloxacin is a fluoroquinolone antibiotic with similar activity to ciprofloxacin.

Chemical Structure

Amifloxacin
Amifloxacin
CAS#86393-37-5 (free base)

Theoretical Analysis

MedKoo Cat#: 573846

Name: Amifloxacin

CAS#: 86393-37-5 (free base)

Chemical Formula: C16H19FN4O3

Exact Mass: 334.1441

Molecular Weight: 334.35

Elemental Analysis: C, 57.48; H, 5.73; F, 5.68; N, 16.76; O, 14.36

Price and Availability

Size Price Availability Quantity
5mg USD 350.00 2 Weeks
10mg USD 550.00 2 Weeks
25mg USD 950.00 2 Weeks
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Related CAS #
88036-80-0 (mesylate) 86393-37-5 (free base)
Synonym
Amifloxacin; Amifloxacine; Win 49375; Win49375; Win-49375;
IUPAC/Chemical Name
3-Quinolinecarboxylic acid, 6-fluoro-1,4-dihydro-1-(methylamino)-7-(4-methyl-1-piperazinyl)-4-oxo-
InChi Key
RUXPNBWPIRDVTH-UHFFFAOYSA-N
InChi Code
1S/C16H19FN4O3/c1-18-21-9-11(16(23)24)15(22)10-7-12(17)14(8-13(10)21)20-5-3-19(2)4-6-20/h7-9,18H,3-6H2,1-2H3,(H,23,24)
SMILES Code
CNn1cc(c(=O)c2c1cc(c(c2)F)N3CCN(CC3)C)C(=O)O
Appearance
Solid powder
Purity
>97% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 334.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Venezia RA, Prymas LA, Shayegani A, Yocum DM. In vitro activities of amifloxacin and two of its metabolites. Antimicrob Agents Chemother. 1989 May;33(5):762-6. PubMed PMID: 2751287; PubMed Central PMCID: PMC172529. 2: Iravani A, Welty GS, Newton BR, Richard GA. Effects of changes in pH, medium, and inoculum size on the in vitro activity of amifloxacin against urinary isolates of Staphylococcus saprophyticus and Escherichia coli. Antimicrob Agents Chemother. 1985 Apr;27(4):449-51. PubMed PMID: 3890724; PubMed Central PMCID: PMC180072.