R 151885 | CAS#76674-14-1 | inhibitor

MedKoo Cat#: 585079 | Name: R 151885

Description:

WARNING: This product is for research use only, not for human or veterinary use.

R 151885 delays ovulation in rats.

Chemical Structure

R 151885

CAS#76674-14-1

Theoretical Analysis

MedKoo Cat#: 585079

Name: R 151885

CAS#: 76674-14-1

Chemical Formula: C16H13F2N3O

Exact Mass: 301.1027

Molecular Weight: 301.30

Elemental Analysis: C, 63.78; H, 4.35; F, 12.61; N, 13.95; O, 5.31

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

R 151885; R151885; R-151885

IUPAC/Chemical Name

1H-1,2,4-Triazole-1-ethanol, alpha,alpha-bis(4-fluorophenyl)-

InChi Key

OGZYWIZILQBEJI-UHFFFAOYSA-N

InChi Code

InChI=1S/C16H13F2N3O/c17-14-5-1-12(2-6-14)16(22,9-21-11-19-10-20-21)13-3-7-15(18)8-4-13/h1-8,10-11,22H,9H2

SMILES Code

OC(C1=CC=C(F)C=C1)(C2=CC=C(F)C=C2)CN3N=CN=C3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 301.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Milne CM, Hasmall RL, Russell A, Watson SC, Vaughan Z, Middleton MC. Reduced estradiol production by a substituted triazole results in delayed ovulation in rats. Toxicol Appl Pharmacol. 1987 Sep 30;90(3):427-35. PubMed PMID: 3310336. 2: Wickings EJ, Middleton MC, Hillier SG. Non-steroidal inhibition of granulosa cell aromatase activity in vitro. J Steroid Biochem. 1987 Jun;26(6):641-6. PubMed PMID: 3112466. 3: Middleton MC, Milne CM, Moreland S, Hasmall RL. Ovulation in rats is delayed by a substituted triazole. Toxicol Appl Pharmacol. 1986 Apr;83(2):230-9. PubMed PMID: 3083533.