C-BVDU | CAS# 91661-22-2 | Antiviral| MedKoo

MedKoo Cat#: 576913 | Name: C-BVDU

Description:

WARNING: This product is for research use only, not for human or veterinary use.

C-BVDU is a cyclopentenylcytosine with activity against herpes simplex virus type l (HSV-1) and varicella zoster virus (VZV, chicken pox and shingles) in-vitro and in-vivo.

Chemical Structure

C-BVDU

CAS#91661-22-2

Theoretical Analysis

MedKoo Cat#: 576913

Name: C-BVDU

CAS#: 91661-22-2

Chemical Formula: C12H15BrN2O4

Exact Mass: 330.0215

Molecular Weight: 331.17

Elemental Analysis: C, 43.52; H, 4.57; Br, 24.13; N, 8.46; O, 19.32

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Carbocyclic BVDU; C-BVDU; C BVDU; CBVDU

IUPAC/Chemical Name

1-(3-hydroxy-4-(hydroxymethyl)-cyclopentyl)-5-(2-bromovinyl)-2,4-(1H,3H)-pyrimidinedione

InChi Key

KAVDAMFOTJIBCK-OWOJBTEDSA-N

InChi Code

InChI=1S/C12H15BrN2O4/c13-2-1-7-5-15(12(19)14-11(7)18)9-3-8(6-16)10(17)4-9/h1-2,5,8-10,16-17H,3-4,6H2,(H,14,18,19)/b2-1+

SMILES Code

O=C1NC(C(/C=C/Br)=CN1C2CC(O)C(CO)C2)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 331.17 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Balzarini J, De Clercq E, Baumgartner H, Bodenteich M, Griengl H. Carbocyclic 5-iodo-2'-deoxyuridine (C-IDU) and carbocyclic (E)-5-(2-bromovinyl)-2'-deoxyuridine (C-BVDU) as unique examples of chiral molecules where the two enantiomeric forms are biologically active: interaction of the (+)- and (-)-enantiomers of C-IDU and C-BVDU with the thymidine kinase of herpes simplex virus type 1. Mol Pharmacol. 1990 Mar;37(3):395-401. PMID: 2156153. 2. De Clercq E. Selective virus inhibitors. Microbiologica. 1990 Apr;13(2):165-78. PMID: 1693749. 3. Balzarini J, De Clercq E, Verbruggen A, Crumpacker C, Ayusawa D, Seno T. Increased sensitivity of thymidine kinase-deficient (TK-) tumor cell lines to the cell growth inhibitory effects of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and related compounds. Anticancer Res. 1986 Sep-Oct;6(5):1077-84. PMID: 2432829.