MedKoo Cat#: 124793 | Name: CZL55
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CZL55 is a caspase-1 inhibitor. CZL55 can be used for the research of febrile seizures (FS)

Chemical Structure

CZL55
CZL55
CAS#667408-87-9

Theoretical Analysis

MedKoo Cat#: 124793

Name: CZL55

CAS#: 667408-87-9

Chemical Formula: C20H22N2O6

Exact Mass: 386.1478

Molecular Weight: 386.40

Elemental Analysis: C, 62.17; H, 5.74; N, 7.25; O, 24.84

Price and Availability

Size Price Availability Quantity
100mg USD 950.00 2 Weeks
200mg USD 1,650.00 2 Weeks
500mg USD 2,650.00 2 Weeks
1g USD 3,950.00 2 Weeks
2g USD 6,850.00 2 Weeks
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Related CAS #
No Data
Synonym
CZL55; CZL-55; CZL 55
IUPAC/Chemical Name
5-((3-((2,4-dimethoxyphenyl)carbamoyl)phenyl)amino)-5-oxopentanoic acid
InChi Key
IXPHIUQELSUDNK-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H22N2O6/c1-27-15-9-10-16(17(12-15)28-2)22-20(26)13-5-3-6-14(11-13)21-18(23)7-4-8-19(24)25/h3,5-6,9-12H,4,7-8H2,1-2H3,(H,21,23)(H,22,26)(H,24,25)
SMILES Code
O=C(O)CCCC(NC1=CC=CC(C(NC2=CC=C(OC)C=C2OC)=O)=C1)=O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 386.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Tang Y, Feng B, Wang Y, Sun H, You Y, Yu J, Chen B, Xu C, Ruan Y, Cui S, Hu G, Hou T, Chen Z. Structure-based discovery of CZL80, a caspase-1 inhibitor with therapeutic potential for febrile seizures and later enhanced epileptogenic susceptibility. Br J Pharmacol. 2020 Aug;177(15):3519-3534. doi: 10.1111/bph.15076. Epub 2020 Jun 1. PMID: 32346861; PMCID: PMC7348094.