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MedKoo Cat#: 573780 | Name: AMD-3329 hydrobromide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AMD-3329 hydrobromide is a biochemical in the class of potent and selective anti-HIV-1 and HIV-2 agents that inhibit virus replication by binding to the chemokine receptor CXCR4, the co-receptor for entry of X4 viruses.

Chemical Structure

AMD-3329 hydrobromide
AMD-3329 hydrobromide
CAS#170861-77-5

Theoretical Analysis

MedKoo Cat#: 573780

Name: AMD-3329 hydrobromide

CAS#: 170861-77-5

Chemical Formula: C34H58Br8N8

Exact Mass: 1209.8251

Molecular Weight: 1218.13

Elemental Analysis: C, 33.52; H, 4.80; Br, 52.48; N, 9.20

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
170861-87-7 (free base)
Synonym
AMD-3329 hydrobromide, AMD 3329 hydrobromide, AMD3329 hydrobromide
IUPAC/Chemical Name
4,7,10,17-Tetraazabicyclo(11.3.1)heptadeca-1(17),13,15-triene, 7,7'-(1,4-phenylenebis(methylene))bis-, octahydrobromide
InChi Key
PTUYNGRETVWEER-UHFFFAOYSA-N
InChi Code
1S/C34H50N8.8BrH/c1-3-31-11-15-35-19-23-41(24-20-36-16-12-32(4-1)39-31)27-29-7-9-30(10-8-29)28-42-25-21-37-17-13-33-5-2-6-34(40-33)14-18-38-22-26-42;;;;;;;;/h1-10,35-38H,11-28H2;8*1H
SMILES Code
c1cc2nc(c1)CCNCCN(CCNCC2)Cc3ccc(cc3)CN4CCNCCc5cccc(n5)CCNCC4.Br.Br.Br.Br.Br.Br.Br.Br
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 1,218.13 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Bridger GJ, Skerlj RT, Padmanabhan S, Martellucci SA, Henson GW, Struyf S, Witvrouw M, Schols D, De Clercq E. Synthesis and structure-activity relationships of phenylenebis(methylene)-linked bis-azamacrocycles that inhibit HIV-1 and HIV-2 replication by antagonism of the chemokine receptor CXCR4. J Med Chem. 1999 Sep 23;42(19):3971-81. PubMed PMID: 10508445.