Related CAS #
562-26-5 (free base); 3627-49-4 (HCl)
Synonym
Phenoperidine hydrochloride; Phenoperidine HCl; SC-9369; SC9369; SC 9369
IUPAC/Chemical Name
4-Phenyl-4-carbethoxy-1-(3-hydroxy-3-phenylpropyl)piperidine hydrochloride
InChi Key
HGEAGOBQOIMDQV-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H29NO3.ClH/c1-2-27-22(26)23(20-11-7-4-8-12-20)14-17-24(18-15-23)16-13-21(25)19-9-5-3-6-10-19;/h3-12,21,25H,2,13-18H2,1H3;1H
SMILES Code
OC(C1=CC=CC=C1)CCN2CCC(C(OCC)=O)(C3=CC=CC=C3)CC2.[H]Cl
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
403.95
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Calvey TN, Williams NE. Pharmacokinetics of phenoperidine. Br J Anaesth. 1986 Jul;58(7):821-2. doi: 10.1093/bja/58.7.821. PMID: 3730227.
2: de Castro J, Van de Water A, Wouters L, Xhonneux R, Reneman R, Kay B. Comparative study of cardiovascular, neurological and metabolic side effects of 8 narcotics in dogs. Pethidine, piritramide, morphine, phenoperidine, fentanyl, R 39 209, sufentanil, R 34 995. I. Comparative study on the acute toxicity and hemodynamic effects of the narcotics in high and massive doses in curarised and mechanically ventilated dogs. Acta Anaesthesiol Belg. 1979 Mar;30(1):5-54. PMID: 382728.
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4: Steele PR, Masheter HC. Phenoperidine and droperidol as premedicants. A controlled study in ophthalmic surgical procedures in combination with retrobulbar block. Anaesthesia. 1971 Jul;26(3):311-7. doi: 10.1111/j.1365-2044.1971.tb04791.x. PMID: 5090226.
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7: Kortas J, Uherek-Straszko H. Neuroleptoanalgezja [Neuroleptoanalgesia]. Pol Tyg Lek. 1969 Jan 27;24(4):149-50. Polish. PMID: 5776786.
8: Vourc'h G, Boissier A, Kreuscher, Sabathie, Simon, Viars, Winckler. La neuroleptanalgésie [Neuroleptoanalgesia]. Cah Anesthesiol. 1967 Dec;15(8):929-77. French. PMID: 5622936.
9: De Blasi A, Appiani L, Brienza A, Gasparetto A, Manni C, Maritano M, Mazzarella B, Morpurgo V. La neuroleptoanalgesia [Neuroleptoanalgesia]. Minerva Anestesiol. 1968 Aug;34(8):933-90. Italian. PMID: 5736580.
10: Fischler M, Levron JC, Trang H, Brodaty D, Dubois C, Guilmet D, Vourc'h G. Pharmacokinetics of phenoperidine in patients undergoing cardiopulmonary bypass. Br J Anaesth. 1985 Sep;57(9):877-82. doi: 10.1093/bja/57.9.877. PMID: 4027104.
