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MedKoo Cat#: 558311 | Name: Phenmedipham
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Phenmedipham is a herbicide, especially in the growing of sugar beet and strawberries.

Chemical Structure

Phenmedipham
Phenmedipham
CAS#13684-63-4

Theoretical Analysis

MedKoo Cat#: 558311

Name: Phenmedipham

CAS#: 13684-63-4

Chemical Formula: C16H16N2O4

Exact Mass: 300.1110

Molecular Weight: 300.31

Elemental Analysis: C, 63.99; H, 5.37; N, 9.33; O, 21.31

Price and Availability

Size Price Availability Quantity
100mg USD 450.00 2 Weeks
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Related CAS #
No Data
Synonym
Phenmedipham; Fenmedifam; HSDB 1402; Kemifam;
IUPAC/Chemical Name
Carbamic acid, (3-methylphenyl)-, 3-((methoxycarbonyl)amino)phenyl ester
InChi Key
IDOWTHOLJBTAFI-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H16N2O4/c1-11-5-3-6-12(9-11)18-16(20)22-14-8-4-7-13(10-14)17-15(19)21-2/h3-10H,1-2H3,(H,17,19)(H,18,20)
SMILES Code
O=C(OC1=CC=CC(NC(OC)=O)=C1)NC2=CC=CC(C)=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Product Data
Instruction
View handling instruction
Biological target:
Phenmedipham is a carbamate herbicide.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 300.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: Morsi R, Ghoudi K, Meetani MA. Determination and health risk assessment of carbamate pesticide residues in date palm fruits (Phoenix dactylifera) using QuEChERS method and UHPLC-MS/MS. Sci Rep. 2024 Jun 6;14(1):13064. doi: 10.1038/s41598-024-63704-6. PMID: 38844596; PMCID: PMC11156656. 2: Cheng Z, Gao H, Xiong Y, Wei L, Ma T, Wang L, Gao S, Jiang X, Li J, Wang Y, Hou Z, Lu Z. Dissipation behaviours, residues, and health risk of six herbicides in sugar beets under field conditions. Ecotoxicol Environ Saf. 2024 Apr 1;274:116199. doi: 10.1016/j.ecoenv.2024.116199. Epub 2024 Mar 15. PMID: 38492485. 3: Zilnik G, Bergeron PE, Chuang A, Diepenbrock L, Hanel A, Middleton E, Moretti E, Schmidt-Jeffris R. Meta-Analysis of Herbicide Non-Target Effects on Pest Natural Enemies. Insects. 2023 Sep 26;14(10):787. doi: 10.3390/insects14100787. PMID: 37887799; PMCID: PMC10607068. 4: McGinley J, Harmon O'Driscoll J, Healy MG, Ryan PC, Mellander PE, Morrison L, Callery O, Siggins A. An assessment of potential pesticide transmission, considering the combined impact of soil texture and pesticide properties: A meta-analysis. Soil Use Manag. 2022 Apr;38(2):1162-1171. doi: 10.1111/sum.12794. Epub 2022 Mar 8. PMID: 35915848; PMCID: PMC9313564. 5: Santos J, Barreto A, Sousa ÉML, Calisto V, Amorim MJB, Maria VL. The role of nanoplastics on the toxicity of the herbicide phenmedipham, using Danio rerio embryos as model organisms. Environ Pollut. 2022 Jun 15;303:119166. doi: 10.1016/j.envpol.2022.119166. Epub 2022 Mar 16. PMID: 35306087. 6: EFSA (European Food Safety Authority); Anastassiadou M, Bellisai G, Bernasconi G, Brancato A, Carrasco Cabrera L, Ferreira L, Greco L, Jarrah S, Kazocina A, Leuschner R, Magrans JO, Miron I, Nave S, Pedersen R, Reich H, Santos M, Scarlato AP, Theobald A, Vagenende B, Verani A. Modification of the existing maximum residue level for phenmedipham in celeriac. EFSA J. 2021 Mar 22;19(3):e06482. doi: 10.2903/j.efsa.2021.6482. PMID: 33777235; PMCID: PMC7983034. 7: European Food Safety Authority (EFSA); Anastassiadou M, Bernasconi G, Brancato A, Carrasco Cabrera L, Ferreira L, Greco L, Jarrah S, Kazocina A, Leuschner R, Magrans JO, Miron I, Nave S, Pedersen R, Reich H, Rojas A, Santos M, Scarlato AP, Theobald A, Vagenende B, Verani A. Modification of the existing maximum residue level for phenmedipham in strawberries. EFSA J. 2021 Feb 26;19(2):e06436. doi: 10.2903/j.efsa.2021.6436. PMID: 33680136; PMCID: PMC7908043. 8: Pujar NK, Laad S, Premakshi HG, Pattar SV, Mirjankar M, Kamanavalli CM. Biodegradation of phenmedipham by novel Ochrobactrum anthropi NC-1. 3 Biotech. 2019 Feb;9(2):52. doi: 10.1007/s13205-019-1589-8. Epub 2019 Jan 25. PMID: 30729076; PMCID: PMC6346688. 9: European Food Safety Authority (EFSA); Arena M, Auteri D, Barmaz S, Bellisai G, Brancato A, Brocca D, Bura L, Byers H, Chiusolo A, Court Marques D, Crivellente F, De Lentdecker C, Egsmose M, Erdos Z, Fait G, Ferreira L, Goumenou M, Greco L, Ippolito A, Istace F, Jarrah S, Kardassi D, Leuschner R, Lythgo C, Magrans JO, Medina P, Miron I, Molnar T, Nougadere A, Padovani L, Parra Morte JM, Pedersen R, Reich H, Sacchi A, Santos M, Serafimova R, Sharp R, Stanek A, Streissl F, Sturma J, Szentes C, Tarazona J, Terron A, Theobald A, Vagenende B, Verani A, Villamar-Bouza L. Peer review of the pesticide risk assessment of the active substance phenmedipham. EFSA J. 2018 Jan 31;16(1):e05151. doi: 10.2903/j.efsa.2018.5151. PMID: 32625695; PMCID: PMC7009510. 10: Vidal T, Pereira JL, Abrantes N, Soares AM, Gonçalves F. Reproductive and developmental toxicity of the herbicide Betanal® Expert and corresponding active ingredients to Daphnia spp. Environ Sci Pollut Res Int. 2016 Jul;23(13):13276-87. doi: 10.1007/s11356-016-6492-9. Epub 2016 Mar 29. PMID: 27023815. 11: Bori J, Riva MC. An Alternative Approach to Assess the Habitat Selection of Folsomia candida in Contaminated Soils. Bull Environ Contam Toxicol. 2015 Nov;95(5):670-4. doi: 10.1007/s00128-015-1647-9. Epub 2015 Sep 9. PMID: 26350730. 12: Novais SC, Howcroft CF, Carreto L, Pereira PM, Santos MA, De Coen W, Soares AM, Amorim MJ. Differential gene expression analysis in Enchytraeus albidus exposed to natural and chemical stressors at different exposure periods. Ecotoxicology. 2012 Jan;21(1):213-24. doi: 10.1007/s10646-011-0780-4. Epub 2011 Sep 4. PMID: 21892792. 13: Vidal T, Abrantes N, Gonçalves AM, Gonçalves F. Acute and chronic toxicity of Betanal(®)Expert and its active ingredients on nontarget aquatic organisms from different trophic levels. Environ Toxicol. 2012 Sep;27(9):537-48. doi: 10.1002/tox.20671. Epub 2011 Mar 3. PMID: 21374783. 14: Amorim MJ, Novais SC, Van Der Ven K, Vandenbrouck T, Soares AM, De Coen W. Development of a microarray for Enchytraeus albidus (Oligochaeta): preliminary tool with diverse applications. Environ Toxicol Chem. 2011 Jun;30(6):1395-402. doi: 10.1002/etc.512. Epub 2011 Mar 31. PMID: 21360579. 15: Howcroft CF, Gravato C, Amorim MJ, Novais SC, Soares AM, Guilhermino L. Biochemical characterization of cholinesterases in Enchytraeus albidus and assessment of in vivo and in vitro effects of different soil properties, copper and phenmedipham. Ecotoxicology. 2011 Jan;20(1):119-30. doi: 10.1007/s10646-010-0562-4. Epub 2010 Nov 16. PMID: 21080225. 16: Novais SC, Soares AM, Amorim MJ. Can avoidance in Enchytraeus albidus be used as a screening parameter for pesticides testing? Chemosphere. 2010 Mar;79(2):233-7. doi: 10.1016/j.chemosphere.2010.01.011. Epub 2010 Feb 4. PMID: 20132962. 17: Vincent F, Nguyen MT, Emerling DE, Kelly MG, Duncton MA. Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6793-6. doi: 10.1016/j.bmcl.2009.09.086. Epub 2009 Sep 30. PMID: 19850474. 18: Howcroft CF, Amorim MJ, Gravato C, Guilhermino L, Soares AM. Effects of natural and chemical stressors on Enchytraeus albidus: can oxidative stress parameters be used as fast screening tools for the assessment of different stress impacts in soils? Environ Int. 2009 Feb;35(2):318-24. doi: 10.1016/j.envint.2008.08.004. Epub 2008 Sep 25. PMID: 18819713. 19: Saraji M, Esteki N. Analysis of carbamate pesticides in water samples using single-drop microextraction and gas chromatography-mass spectrometry. Anal Bioanal Chem. 2008 Jun;391(3):1091-100. doi: 10.1007/s00216-008-2087-8. Epub 2008 Apr 16. PMID: 18415085. 20: Amorim MJ, Novais S, Römbke J, Soares AM. Avoidance test with Enchytraeus albidus (Enchytraeidae): effects of different exposure time and soil properties. Environ Pollut. 2008 Sep;155(1):112-6. doi: 10.1016/j.envpol.2007.10.028. Epub 2007 Dec 11. PMID: 18069103.