MedKoo Cat#: 585044 | Name: CM 10
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CM 10 is an ALDH1A inhibitor that depletes CD133+ cancer stem cells.

Chemical Structure

CM 10
CM 10
CAS#692269-09-3

Theoretical Analysis

MedKoo Cat#: 585044

Name: CM 10

CAS#: 692269-09-3

Chemical Formula: C20H23N3O

Exact Mass: 321.1841

Molecular Weight: 321.42

Elemental Analysis: C, 74.74; H, 7.21; N, 13.07; O, 4.98

Price and Availability

Size Price Availability Quantity
25mg USD 350.00 2 Weeks
50mg USD 600.00 2 Weeks
100mg USD 950.00 2 Weeks
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Related CAS #
No Data
Synonym
CM 10; CM10; CM-10
IUPAC/Chemical Name
2-(2-Propen-1-yl)-6-[[(1-propyl-1H-benzimidazol-2-yl)amino]methyl]phenol
InChi Key
ZFHWEWJDCFGRBO-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H23N3O/c1-3-8-15-9-7-10-16(19(15)24)14-21-20-22-17-11-5-6-12-18(17)23(20)13-4-2/h3,5-7,9-12,24H,1,4,8,13-14H2,2H3,(H,21,22)
SMILES Code
OC1=C(CNC2=NC3=CC=CC=C3N2CCC)C=CC=C1CC=C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 321.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Chefetz et al (2019) A pan-ALDH1A inhibitor induces necroptosis in ovarian cancer stem-like cells. Cell Rep. 26 3061 PMID: 30865894 Morgan & Hurley (2015) Development of a high-throughput in vitro assay to identify selective inhibitors for human ALDH1A1. Chem.Biol.Interact. 234 29 PMID: 25450233