MedKoo Cat#: 463002 | Name: Dimorpholamine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dimorpholamine is a member of morpholines and a member of ureas. It is also a respiratory stimulant.

Chemical Structure

Dimorpholamine
Dimorpholamine
CAS#119-48-2

Theoretical Analysis

MedKoo Cat#: 463002

Name: Dimorpholamine

CAS#: 119-48-2

Chemical Formula: C20H38N4O4

Exact Mass: 398.2893

Molecular Weight: 398.55

Elemental Analysis: C, 60.27; H, 9.61; N, 14.06; O, 16.06

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Amipan T; Atmurin; Prontodin; Theraleptique; Theraptique;
IUPAC/Chemical Name
N,N'-(ethane-1,2-diyl)bis(N-butylmorpholine-4-carboxamide)
InChi Key
HZTMGWSBSDLALI-UHFFFAOYSA-N
InChi Code
InChI=1S/C20H38N4O4/c1-3-5-7-21(19(25)23-11-15-27-16-12-23)9-10-22(8-6-4-2)20(26)24-13-17-28-18-14-24/h3-18H2,1-2H3
SMILES Code
CCCCN(C(N1CCOCC1)=O)CCN(C(N2CCOCC2)=O)CCCC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 398.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kazama K, Okada M, Hara Y, Yamawaki H. A novel adipocytokine, omentin, inhibits agonists-induced increases of blood pressure in rats. J Vet Med Sci. 2013;75(8):1029-34. doi: 10.1292/jvms.12-0537. Epub 2013 Apr 1. PMID: 23546685. 2: Iizuka H, Sasaki K, Odagiri N, Obo M, Imaizumi M, Atai H. Measurement of respiratory function using whole-body plethysmography in unanesthetized and unrestrained nonhuman primates. J Toxicol Sci. 2010 Dec;35(6):863-70. doi: 10.2131/jts.35.863. PMID: 21139336. 3: Kigasawa K, Saitoh K, Tanizaki A, Ohkubo K, Iirino O. A new method for measuring respiration in the conscious mouse. J Pharmacol Methods. 1984 Oct;12(3):183-9. doi: 10.1016/0160-5402(84)90058-5. PMID: 6443137. 4: Kigasawa K, Saitoh K, Iwadate K, Ohkubo K, Irino O. A method for monitoring ADP-induced thromboembolism in mice. Thromb Res. 1984 Aug 1;35(3):311-8. doi: 10.1016/0049-3848(84)90362-1. PMID: 6463962. 5: Hironaka T, Ikari Y, Morimoto S. Ionic mechanism of the resting membrane depolarization of frog sartorius muscle induced by dimorpholamine. Jpn J Pharmacol. 1980 Jun;30(3):279-85. doi: 10.1254/jjp.30.279. PMID: 7452980. 6: Hironaka T, Morimoto S. Effects of dimorpholamine on frog sciatic nerve- sartorius preparation. Jpn J Pharmacol. 1979 Jun;29(3):457-66. doi: 10.1254/jjp.29.457. PMID: 43915. 7: Murai S, Ogura Y. Effect of erabutoxin on respiration of rabbits. Jpn J Pharmacol. 1977 Oct;27(5):721-6. doi: 10.1254/jjp.27.721. PMID: 592560. 8: Azuma H, Miyazawa T. [Effects of 1-ethyl-4-(2-morpholinoethyl)-3, 3-diphenyl-2-pyrrolidinone hydrochloride hydrate (doxapram) on the transmural stimulation and reactiontonicotine of the isolated guinea pig heart atrium]. Nihon Yakurigaku Zasshi. 1975 Nov;71(8):823-31. Japanese. PMID: 1240832. 9: Yasuda I, Iwatsuki K. [Effect of doxapram(Dopram) and dimorpholamine (Theraptique) on arrhythmia an]. Masui. 1974 Oct;23(11):1067-71. Japanese. PMID: 4475120. 10: Hironaka T, Otsuka M. The effect of dimorpholamine on crayfish neuromuscular junction. Neuropharmacology. 1972 Jul;11(4):573-84. doi: 10.1016/0028-3908(72)90013-5. PMID: 4403079. 11: Hironaka T. [Effect of dimorpholamine (Th 1064) on crayfish neuromuscular junction]. Nihon Yakurigaku Zasshi. 1970 May 20;66(3):293-303. Japanese. PMID: 5465625. 12: Makabe T. [Influence of pentetrazol (PTZ), dimorpholamine (DMP) and trans- pi-oxocamphor (t-pi-oc) on the ventricular pacemaker of guinea pigs]. Nihon Yakurigaku Zasshi. 1969 May 20;65(3):220-7. Japanese. doi: 10.1254/fpj.65.220. PMID: 5388117. 13: Imai S, Murase H, Takeda K, Katori M, Shigei T. Cardiac action of dimorpholamine. Jpn J Pharmacol. 1966 Mar;16(1):110-6. doi: 10.1254/jjp.16.110. PMID: 4381205. 14: Sakuma A, Kato H, Saji Y. Effects of dimorpholamine on blood pressure. Jpn J Pharmacol. 1965 Dec;15(4):386-94. doi: 10.1254/jjp.15.386. PMID: 4380026.