MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 534946 | Name: Merocil

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Merocil is a bioactive chemical.

Chemical Structure

Merocil
CAS#143413-72-3

Theoretical Analysis

MedKoo Cat#: 534946

Name: Merocil

CAS#: 143413-72-3

Chemical Formula: C13H22N2O4S

Exact Mass: 302.1300

Molecular Weight: 302.39

Elemental Analysis: C, 51.64; H, 7.33; N, 9.26; O, 21.16; S, 10.60

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Merocil
IUPAC/Chemical Name
4,6(1H,5H)-Pyrimidinedione, 1,3-dibutyldihydro-5-hydroxy-5-methoxy-2-thioxo-
InChi Key
WUYOSDQTOAOHAL-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H22N2O4S/c1-4-6-8-14-10(16)13(18,19-3)11(17)15(12(14)20)9-7-5-2/h18H,4-9H2,1-3H3
SMILES Code
O=C(C(OC)(O)C(N1CCCC)=O)N(CCCC)C1=S
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 302.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Akkan S, Çorbacıoğlu ŞK, Aytar H, Emektar E, Dağar S, Çevik Y. Evaluating Effectiveness of Nasal Compression With Tranexamic Acid Compared With Simple Nasal Compression and Merocel Packing: A Randomized Controlled Trial. Ann Emerg Med. 2019 Jul;74(1):72-78. doi: 10.1016/j.annemergmed.2019.03.030. Epub 2019 May 9. PMID: 31080025. 2: Kaur J, Singh M, Kaur I, Singh A, Goyal S. A comparative study of gloved versus ungloved merocel® as nasal pack after septoplasty. Niger J Clin Pract. 2018 Nov;21(11):1391-1395. doi: 10.4103/njcp.njcp_414_17. PMID: 30417834. 3: Kim SW, Park CW, Kim JT, Kim YH. Merocel semicompressive dressing to prevent donor-site hematoma on the conchal cartilage graft. J Craniofac Surg. 2012 Jan;23(1):57-60. doi: 10.1097/SCS.0b013e318240c908. PMID: 22337374. 4: Romano A, Salzano G, Dell'Aversana Orabona G, Cama A, Petrocelli M, Piombino P, Schonauer F, Iaconetta G, Salzano FA, Califano L. Comparative study between biodegradable nasopore (BNP) and Merocel hemox 10 cm after septo-turbinoplasty procedure. Eur Rev Med Pharmacol Sci. 2017 Feb;21(4):669-673. PMID: 28272718. 5: Abu Eta R, Eviatar E, Pitaro J, Gavriel H. Post-turbinectomy nasal packing with Merocel versus glove finger Merocel: A prospective, randomized, controlled trial. Ear Nose Throat J. 2018 Mar;97(3):64-68. doi: 10.1177/014556131809700320. PMID: 29554399. 6: Wang J, Cai C, Wang S. Merocel versus Nasopore for nasal packing: a meta- analysis of randomized controlled trials. PLoS One. 2014 Apr 7;9(4):e93959. doi: 10.1371/journal.pone.0093959. PMID: 24710428; PMCID: PMC3977961. 7: Hesham A, Ghali A. Rapid Rhino versus Merocel nasal packs in septal surgery. J Laryngol Otol. 2011 Dec;125(12):1244-6. doi: 10.1017/S0022215111002179. Epub 2011 Aug 19. PMID: 21854674. 8: Tan WJ, Yusof S. The Merocel anal pack: an innovative use for symptomatic hemorrhoids. Tech Coloproctol. 2014 Nov;18(11):1127-8. doi: 10.1007/s10151-014-1211-3. Epub 2014 Aug 26. PMID: 25154753. 9: Celebi S, Caglar E, Develioglu ON, Topak M, Yalcin E, Kulekci M. The effect of the duration of merocel in a glove finger on postoperative morbidity. J Craniofac Surg. 2013 Jul;24(4):1232-4. doi: 10.1097/SCS.0b013e31828a72a2. PMID: 23851776. 10: Singh R, Sood N, Kerai S, Puri A. Use of Merocel® aids in prevention of nasal pressure ulcers following nasal intubation: Case series of 33 patients. Indian J Anaesth. 2017 Jun;61(6):513-515. doi: 10.4103/ija.IJA_26_17. PMID: 28655961; PMCID: PMC5474924. 11: Manji J, Habib AR, Macias-Valle L, Finkelstein A, Alsaleh S, Dadgostar A, Al-Asousi F, Okpaleke C, Javer AR. Comparing the efficacy of Silastic and gloved-Merocel middle meatal spacers for functional endoscopic sinus surgery: a randomized controlled trial. Int Forum Allergy Rhinol. 2018 Mar 30. doi: 10.1002/alr.22119. Epub ahead of print. PMID: 29601150. 12: Chang EH, Alandejani T, Akbari E, Ostry A, Javer A. Double-blinded, randomized, controlled trial of medicated versus nonmedicated merocel sponges for functional endoscopic sinus surgery. J Otolaryngol Head Neck Surg. 2011 Feb;40 Suppl 1:S14-9. PMID: 21453656. 13: Titiz A, Zeyrek T, Ozcan M, Sabuncuoglu B, Yilmaz YF, Unal A. The effects of merocel and glove finger tampon applications on the nasal septum mucosa of rabbits. Rhinology. 2008 Jun;46(2):112-5. PMID: 18575011. 14: Akbari E, Philpott CM, Ostry AJ, Clark A, Javer AR. A double-blind randomised controlled trial of gloved versus ungloved merocel middle meatal spacers for endoscopic sinus surgery. Rhinology. 2012 Sep;50(3):306-10. doi: 10.4193/Rhino10.215. PMID: 22888489. 15: Çelik Ö, Boyaci Z, Ateşpare A, Develioğlu O, Karaca Ç, Çaglar E, Vural Ç. The effect of duration of merocel in glove finger with tetracaine solution on septoplasty morbidity. J Craniofac Surg. 2013 Nov;24(6):1931-4. doi: 10.1097/01.SCS.0000435809.68641.6c. PMID: 24220376. 16: Bresnihan M, Mehigan B, Curran A. An evaluation of Merocel and Series 5000 nasal packs in patients following nasal surgery: a prospective randomised trial. Clin Otolaryngol. 2007 Oct;32(5):352-5. doi: 10.1111/j.1749-4486.2007.01517.x. PMID: 17883554. 17: Alshehri WM, Alwehaibi WM, Ahmed MW, Albathi A, Alqahtani B. Merocel Surgicel Wrap Technique to Manage Diffuse Epistaxis in Patients with Comorbidities. Int J Otolaryngol. 2020 Mar 22;2020:8272914. doi: 10.1155/2020/8272914. PMID: 32280348; PMCID: PMC7125479. 18: Bingöl F, Budak A, Şimşek E, Kılıç K, Bingöl BÖ. Comparison of Early-period Results of Nasal Splint and Merocel Nasal Packs in Septoplasty. Turk Arch Otorhinolaryngol. 2017 Sep;55(3):136-139. doi: 10.5152/tao.2017.2259. Epub 2017 Aug 16. PMID: 29392071; PMCID: PMC5782992. 19: Stew B, Fishpool SJ, Moorhouse T, Williams H. Rapid Rhino versus Merocel nasal packs in septal surgery. J Laryngol Otol. 2012 Jun;126(6):651; author reply 651. doi: 10.1017/S0022215112000278. Epub 2012 Mar 26. PMID: 22449802. 20: Visvanathan V. Anterior nasal packing with merocel: a modification. Clin Otolaryngol. 2008 Oct;33(5):510. doi: 10.1111/j.1749-4486.2008.01721.x. PMID: 18983409.