MedKoo Cat#: 565624 | Name: MDI-2268

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MDI-2268 is a novel potent inhibitor of plasminogen activator inhibitor type-1 (pai-1)

Chemical Structure

MDI-2268
MDI-2268
CAS#1609176-50-2

Theoretical Analysis

MedKoo Cat#: 565624

Name: MDI-2268

CAS#: 1609176-50-2

Chemical Formula: C10H10F3N3O3

Exact Mass: 277.0674

Molecular Weight: 277.20

Elemental Analysis: C, 43.33; H, 3.64; F, 20.56; N, 15.16; O, 17.31

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
MDI-2268; MDI 2268; MDI2268
IUPAC/Chemical Name
2-Hydrazineyl-2-oxo-N-(3-(trifluoromethoxy)benzyl)acetamide
InChi Key
RONKZYYGLIORQV-UHFFFAOYSA-N
InChi Code
InChI=1S/C10H10F3N3O3/c11-10(12,13)19-7-3-1-2-6(4-7)5-15-8(17)9(18)16-14/h1-4H,5,14H2,(H,15,17)(H,16,18)
SMILES Code
O=C(NCC1=CC=CC(OC(F)(F)F)=C1)C(NN)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 277.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Reinke AA, Li SH, Warnock M, Shaydakov ME, Guntaka NS, Su EJ, Diaz JA, Emal CD, Lawrence DA. Dual-reporter high-throughput screen for small-molecule in vivo inhibitors of plasminogen activator inhibitor type-1 yields a clinical lead candidate. J Biol Chem. 2019 Feb 1;294(5):1464-1477. doi: 10.1074/jbc.RA118.004885. Epub 2018 Dec 3. PubMed PMID: 30510136; PubMed Central PMCID: PMC6364767.