MedKoo Cat#: 565514 | Name: HS220

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Bis-2-AI Adjuvant-2 is a novel adjuvant to repurpose azithromycin for use against pseudomonas aeruginosa, exhibiting a 1024-fold reduction in the minimum inhibitory concentration of azithromycin in vitro and displays activity in a galleria mellonella model of infection

Chemical Structure

HS220
HS220
CAS#CAS#N/A

Theoretical Analysis

MedKoo Cat#: 565514

Name: HS220

CAS#: CAS#N/A

Chemical Formula: C10H17N7

Exact Mass: 235.1545

Molecular Weight: 235.30

Elemental Analysis: C, 51.05; H, 7.28; N, 41.67

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Bis-2-AI Adjuvant-2; Bis 2 AI Adjuvant 2; Bis2AIAdjuvant2
IUPAC/Chemical Name
5,5'-(4-Aminobutane-1,1-diyl)bis(1H-imidazol-2-amine)
InChi Key
JPKKBZPSPPUUOA-UHFFFAOYSA-N
InChi Code
InChI=1S/C10H17N7/c11-3-1-2-6(7-4-14-9(12)16-7)8-5-15-10(13)17-8/h4-6H,1-3,11H2,(H3,12,14,16)(H3,13,15,17)
SMILES Code
NCCCC(C1=CN=C(N)N1)C2=CN=C(N)N2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 235.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL