MedKoo Cat#: 592581 | Name: Hexapradol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Hexapradol is a new antiulcer drug with a cytoprotective action.

Chemical Structure

Hexapradol
Hexapradol
CAS#15599-37-8

Theoretical Analysis

MedKoo Cat#: 592581

Name: Hexapradol

CAS#: 15599-37-8

Chemical Formula: C19H25NO

Exact Mass: 283.1936

Molecular Weight: 283.42

Elemental Analysis: Chemical Formula: Exact Mass: Molecular Weight: Elemental Analysis: C, 80.52; H, 8.89; N, 4.94; O, 5.65

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Hexapradol
IUPAC/Chemical Name
alpha-(1-Aminohexyl)benzhydrol
InChi Key
ZVRZJTRBWTVKOJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H25NO/c1-2-3-6-15-18(20)19(21,16-11-7-4-8-12-16)17-13-9-5-10-14-17/h4-5,7-14,18,21H,2-3,6,15,20H2,1H3
SMILES Code
OC(C1=CC=CC=C1)(C(N)CCCCC)C2=CC=CC=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 283.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Lumachi B, Dark R. Hexaprazol antagonism to gastric electrical potential fall by acetylsalicylic acid in rat. Drugs Exp Clin Res. 1985; 11 (10): 693-702. PubMed PMID: 3836856. 2: Girometta MA, Loschi L, Ventura P. Quantitation of hexaprazol in human plasma and urine by capillary gas chromatography with nitrogen-sensitive detection. J Chromatogr. 1986 Nov 28; 383 (1): 85-92. PubMed PMID: 3818848. 3: Scuri R, Mondani G, Fantini PL, Dàlla Valle V, Valsecchi B. Hexaprazol: a new antiulcer drug with a cytoprotective action. Boll Chim Farm. 1984 Sep; 123 (9): 425-38. PubMed PMID: 6529496. 4: Kelly NM, Wellejus A, Elbrønd-Bek H, Weidner MS, Jørgensen SH. Synthesis and biological evaluation of Esaprazole analogues showing σ1 binding and neuroprotective properties in vitro. Bioorg Med Chem. 2013 Jun 1; 21 (11): 3334-47. doi: 10.1016 / j.bmc.2013.02.058. Epub 2013 Apr 2. PubMed PMID: 23601816. 5: Zuccari G, Clavenna G, Room A, Viganò T, Crivellari MT, Folco G. Prostaglandins and gastric mucosal protection by esaprazole in rats. Eur J Pharmacol. 1990 Oct 2; 187 (1): 19-25. PubMed PMID: 2272352. 6: From Monte PR, Gullini S, Saggioro A, Beinat L, Castiglioni CL. Esaprazole in the treatment of gastric ulcer: preliminary clinical trial. Drugs Exp Clin Res. 1987; 13 (5): 305-10. PubMed PMID: 3315535. 7: Erembourg L, Reggiani P, Tosi GP, Ferla G, Beinat L. Evaluation of esaprazole activity on basal gastric secretion and on pentagastrin-stimulated secretion healthy volunteers. Int J Clin Pharmacol Res. 1987; 7 (2): 95-100. PubMed PMID: 3583500. 8: Ventura P, Schiavi M, Risoli G. Metabolites of hexaprazole in rat, dog and human urine. Prat. 1984 Jun; 39 (6): 190-8. PubMed PMID: 6745414. 9: Blandizzi C, Christmas G, De Bona M, Del Tacca M. Gastric antisecretory effects of esaprazole in rats. Digestion. 1992; 51 (4): 226-32. PubMed PMID: 1356865. 10: Ardizzone S, Sangaletti O, Ghirardosi C, Bianchi Porro G. Effect of esaprazole on gastric mucosal potential difference after oral administration of aspirin (ASA). J Int Med Res. 1986; 14 (6): 321-4. PubMed PMID: 3803702. 11: Blandizzi C, Mengozzi G, Intorre L, Natale G, Soldani G, Del Tacca M. Inhibitory cholinergic effects of esaprazole on gastric secretion and plasma gastrin levels in the dog. Pharmacology. 1993 Apr; 46 (4): 231-40. PubMed PMID: 8483969. 12: From the Holy PL, Vianello F, Germana B, Dotto P, Laino G, Del Bianco T, Plebani M, Leandro G, Savarino V, Di Mario F. Esaprazole effect on acid, peptic and alkaline secretion in duodenal ulcer patients. Z Gastroenterol. 1993 Jan; 31 (1): 11-4. PubMed PMID: 8447149. 13: Luzzani F, Clavenna G, Zuccari G. Esaprazole, a new antiulcer agent, stimulates gastric mucus output in the rat. Drugs Exp Clin Res. 1989; 15 (9): 417-20. PubMed PMID: 2630253. 14: Coruzzi G, Adami M, Bertaccini G. [Effects of hexaprazole on digestive system parameters in various animal species: in vitro studies]. Prat. 1985 Oct; 40 (10): 324-33. Italian. PubMed PMID: 4065318. 15: Coruzzi G, Adami M, Signorini G, Bertaccini G. [Effects of hexaprazole on digestive system parameters in various animal species: in vivo studies]. Drug Prat. 1985 Oct; 40 (10): 313-23. Italian. PubMed PMID: 4065317. 16: Sabbatini F, Minieri M, Castiglione F, Di Lanno E, Mazzacca G. [Esaprazole vs sulglycotide in the treatment of dyspeptic patients with chronic superficial gastritis of the antrum]. Clin Ter. 1991 Apr 30; 137 (2): 83-9. Italian. PubMed PMID: 1828408.