MedKoo Cat#: 565496 | Name: YUN90389

Description:

WARNING: This product is for research use only, not for human or veterinary use.

YUN90389, also known as PPARalpha/delta-IN-11, is a the first reported pparα/δ dual antagonist. YUN90389 was first reported in Bioorganic & Medicinal Chemistry Letters (2019), 29(3), 503-508. YUN90389 has CAS#1673590-38-9. This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

YUN90389
YUN90389
CAS#1673590-38-9

Theoretical Analysis

MedKoo Cat#: 565496

Name: YUN90389

CAS#: 1673590-38-9

Chemical Formula: C34H29F4N3O4

Exact Mass: 619.2094

Molecular Weight: 619.62

Elemental Analysis: C, 65.91; H, 4.72; F, 12.26; N, 6.78; O, 10.33

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
1673590-38-9 (free base) 2313527-30-7 (sodium)
Synonym
YUN90389; YUN 90389; YUN-90389; PPARalpha/delta-IN-11; PPARalpha/delta IN 11; PPARalpha/deltaIN11
IUPAC/Chemical Name
2-(4-Ethoxy-4'-(3-(4-(2-fluorophenyl)-5-oxo-1-(4-(trifluoromethyl)phenyl)-4,5-dihydro-1H-1,2,4-triazol-3-yl)propyl)-[1,1'-biphenyl]-3-yl)acetic acid
InChi Key
YIUSVSPYCXFTHR-UHFFFAOYSA-N
InChi Code
InChI=1S/C34H29F4N3O4/c1-2-45-30-19-14-24(20-25(30)21-32(42)43)23-12-10-22(11-13-23)6-5-9-31-39-41(27-17-15-26(16-18-27)34(36,37)38)33(44)40(31)29-8-4-3-7-28(29)35/h3-4,7-8,10-20H,2,5-6,9,21H2,1H3,(H,42,43)
SMILES Code
O=C(O)CC1=CC(C2=CC=C(CCCC(N3C4=CC=CC=C4F)=NN(C5=CC=C(C(F)(F)F)C=C5)C3=O)C=C2)=CC=C1OCC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 619.62 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Discovery of potent and selective PPARα​/δ dual antagonists and initial biological studies Quick View Other Sources By Jacintho, Jason D.; Baccei, Christopher S.; Bravo, Yalda; Broadhead, Alex; Chen, Austin; Correa, Lucia; Fischer, Kim; Laffitte, Bryan; Lee, Catherine; Lorrain, Daniel S.; et al From Bioorganic & Medicinal Chemistry Letters (2019), 29(3), 503-508. | Language: English, Database: CAPLUS