MedKoo Cat#: 563413 | Name: 2MeSATP

Description:

WARNING: This product is for research use only, not for human or veterinary use.

2MeSATP is a potent P2y-purine agonist. It acts by half-maximally activating glycogen phosphorylase at 20 nM to be about 25 times more effective than ATP.

Chemical Structure

2MeSATP
2MeSATP
CAS#100020-57-3

Theoretical Analysis

MedKoo Cat#: 563413

Name: 2MeSATP

CAS#: 100020-57-3

Chemical Formula: C11H14N5Na4O13P3S

Exact Mass:

Molecular Weight: 641.19

Elemental Analysis: C, 20.61; H, 2.20; N, 10.92; Na, 14.34; O, 32.44; P, 14.49; S, 5.00

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
2MeSATP; 2-MeS-ATP tetrasodium salt; 2 MeS ATP tetrasodium salt; 2-MeS-ATP tetrasodium salt; 2-MeS ATP 4Na salt;
IUPAC/Chemical Name
2-(Methylthio)adenosine 5'-triphosphate tetrasodium salt
InChi Key
UEEFBRHXFDJPTA-KWIZKVQNSA-J
InChi Code
InChI=1S/C11H18N5O13P3S.4Na/c1-33-11-14-8(12)5-9(15-11)16(3-13-5)10-7(18)6(17)4(27-10)2-26-31(22,23)29-32(24,25)28-30(19,20)21;;;;/h3-4,6-7,10,17-18H,2H2,1H3,(H,22,23)(H,24,25)(H2,12,14,15)(H2,19,20,21);;;;/q;4*+1/p-4/t4-,6-,7-,10-;;;;/m1..../s1
SMILES Code
O[C@@H]([C@H]([C@H](N1C=NC2=C(N=C(SC)N=C21)N)O3)O)[C@H]3COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O.[Na+].[Na+].[Na+].[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 641.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Bennett MR. The discovery of a new class of synaptic transmitters in smooth muscle 50 years ago and amelioration of coronary artery thrombosis. Acta Physiol (Oxf). 2013 Feb;207(2):236-43. doi: 10.1111/apha.12039. Epub 2012 Dec 14. Review. PubMed PMID: 23167304. 2: Nicholas RA. Identification of the P2Y(12) receptor: a novel member of the P2Y family of receptors activated by extracellular nucleotides. Mol Pharmacol. 2001 Sep;60(3):416-20. Review. PubMed PMID: 11502870. 3: Pavenstädt H, Henger A, Briner V, Greger R, Schollmeyer P. Extracellular ATP regulates glomerular endothelial cell function. J Auton Pharmacol. 1996 Dec;16(6):389-91. Review. PubMed PMID: 9131423. 4: Lambrecht G. Design and pharmacology of selective P2-purinoceptor antagonists. J Auton Pharmacol. 1996 Dec;16(6):341-4. Review. PubMed PMID: 9131412. 5: Hillaire-Buys D, Chapal J, Bertrand G, Petit P, Loubatières-Mariani MM. Purinergic receptors on insulin-secreting cells. Fundam Clin Pharmacol. 1994;8(2):117-27. Review. PubMed PMID: 8020870. 6: Keppens S. The complex interaction of ATP and UTP with isolated hepatocytes. How many receptors? Gen Pharmacol. 1993 Mar;24(2):283-9. Review. PubMed PMID: 8482512.