HS-152 is a novel reversible inhibitor of smurf1, directly targeting the catalytic activity of smurf hect domains, significantly blocking auto-ubiquitination and the transfer of ubiquitin from hect domain to the substrates to form isopeptide bond
MedKoo Cat#: 565479
Name: HS-152
CAS#: 2284548-09-8
Chemical Formula: C20H21ClN4O3
Exact Mass: 400.1302
Molecular Weight: 400.86
Elemental Analysis: C, 59.93; H, 5.28; Cl, 8.84; N, 13.98; O, 11.97
The following data is based on the product molecular weight 400.86 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
