MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 584957 | Name: Oxphaman

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Oxphaman is an azomethine that is an inhibitor of lipoxygenases.

Chemical Structure

Oxphaman
Oxphaman
CAS#112851-89-5

Theoretical Analysis

MedKoo Cat#: 584957

Name: Oxphaman

CAS#: 112851-89-5

Chemical Formula: C17H21NO2

Exact Mass: 271.1572

Molecular Weight: 271.36

Elemental Analysis: C, 75.25; H, 7.80; N, 5.16; O, 11.79

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Oxphaman; Zimet 47-79
IUPAC/Chemical Name
1,4-Benzenediol, 2-((tricyclo(3.3.1.13,7)dec-1-ylimino)methyl)-
InChi Key
KSFHABYHDIUGKU-VCHYOVAHSA-N
InChi Code
InChI=1S/C17H21NO2/c19-15-1-2-16(20)14(6-15)10-18-17-7-11-3-12(8-17)5-13(4-11)9-17/h1-2,6,10-13,19-20H,3-5,7-9H2/b18-10+
SMILES Code
OC1=CC=C(O)C=C1/C=N/C2(C3)CC4CC3CC(C4)C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 271.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Bekemeier H, Hirschelmann R. Role of eicosanoids in the kappa-carrageenin rat tail thrombosis. Biomed Biochim Acta. 1988;47(10-11):S260-3. PubMed PMID: 2470355. 2: Bekemeier H, Hirschelmann R, Langner A, Giessler AJ, Krause E, Funke T, Hänsel F, Schmidt K, Zarnack S, Schumann HH, et al. [The pharmacology of the lipoxygenase inhibitors oxphaman (1-(2,5-dihydroxybenzylidene)aminoadamantane) and oxphalin (1-(3,4-dihydroxybenzylidene)-2,4,6-trimethylaniline]. Pharmazie. 1989 Aug;44(8):550-5. German. PubMed PMID: 2512586. 3: Kuhn C, Bekemeier H, Hirschelmann R, Giessler AJ. Action of cyclooxygenase (COX) and lipoxygenase (LOX) inhibitors as well as of oxygen free radical scavengers (OFRS) in the inflammation-induced vasodepression. Biomed Biochim Acta. 1988;47(10-11):S320-3. PubMed PMID: 3150275. 4: Bakathir HA, Giessler J, Hirschelmann R. Rat heart anaphylaxis: influence of mediator antagonists. Gen Pharmacol. 1991;22(4):673-5. PubMed PMID: 1936900. 5: Bekemeier H, Hänsel F, Sänze JU. [The effect of cyclo-oxygenase and lipoxygenase inhibitors on anaphylactic vasodepression ex vivo in mice and rats]. Pharmazie. 1988 Nov;43(11):784-5. German. PubMed PMID: 3150059.