Sarcolysine hydrochloride | CAS# 1465-26-5 | Antineoplastic

MedKoo Cat#: 573629 | Name: Sarcolysine hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sarcolysine hydrochloride, also known as Melphalan HCl, is a nitrogen mustard and alkylating agent that has been studied for use in multiple myeloma therapy.

Chemical Structure

Sarcolysine hydrochloride

CAS#1465-26-5

Theoretical Analysis

MedKoo Cat#: 573629

Name: Sarcolysine hydrochloride

CAS#: 1465-26-5

Chemical Formula: C13H19Cl3N2O2

Exact Mass: 340.0512

Molecular Weight: 341.66

Elemental Analysis: C, 45.70; H, 5.61; Cl, 31.13; N, 8.20; O, 9.37

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

AI3-52155, Alkeran, DL-Phenylalanine mustard hydrochloride, DL-Sarcolysin monohydrochloride, DL-Sarcolysine hydrochloride, Melphalan, Sarcolysine hydrochloride, Sarcolysine HCl

IUPAC/Chemical Name

Alanine, 3-(p-(bis(2-chloroethyl)amino)phenyl)-, hydrochloride, DL

InChi Key

OUUYBRCCFUEMLH-UHFFFAOYSA-N

InChi Code

1S/C13H18Cl2N2O2.ClH/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19;/h1-4,12H,5-9,16H2,(H,18,19);1H

SMILES Code

Cl.NC(Cc1ccc(cc1)N(CCCl)CCCl)C(=O)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 341.66 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Esma F, Salvini M, Troia R, Boccadoro M, Larocca A, Pautasso C. Melphalan hydrochloride for the treatment of multiple myeloma. Expert Opin Pharmacother. 2017 Aug;18(11):1127-1136. doi: 10.1080/14656566.2017.1349102. Epub 2017 Jul 10. Review. PubMed PMID: 28658983. 2: Singh R, Chen J, Miller T, Bergren M, Mallik R. Solution stability of Captisol-stabilized melphalan (Evomela) versus Propylene glycol-based melphalan hydrochloride injection. Pharm Dev Technol. 2018 Dec;23(10):1024-1029. doi: 10.1080/10837450.2016.1265557. Epub 2016 Dec 14. PubMed PMID: 27973975.