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MedKoo Cat#: 573603 | Name: Gitogenin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Gitogenin is an alpha-glucosidase inhibitor.

Chemical Structure

Gitogenin
Gitogenin
CAS#511-96-6

Theoretical Analysis

MedKoo Cat#: 573603

Name: Gitogenin

CAS#: 511-96-6

Chemical Formula: C27H44O4

Exact Mass: 432.3240

Molecular Weight: 432.64

Elemental Analysis: C, 74.96; H, 10.25; O, 14.79

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
AI3-62266, Digin, Gitogenin
IUPAC/Chemical Name
5alpha,22alpha-Spirostane-2alpha,3beta-diol
InChi Key
FWCXELAAYFYCSR-RYKNUXCGSA-N
InChi Code
1S/C27H44O4/c1-15-7-10-27(30-14-15)16(2)24-23(31-27)12-20-18-6-5-17-11-21(28)22(29)13-26(17,4)19(18)8-9-25(20,24)3/h15-24,28-29H,5-14H2,1-4H3/t15-,16+,17+,18-,19+,20+,21-,22-,23+,24+,25+,26+,27-/m1/s1
SMILES Code
C[C@@H]1CC[C@@]2(OC1)O[C@H]3C[C@H]4[C@@H]5CC[C@H]6C[C@@H](O)[C@H](O)C[C@]6(C)[C@H]5CC[C@]4(C)[C@H]3[C@@H]2C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 432.64 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Panda S, Kar A. Corrigendum to "Role of a gitogenin-type steroidal saponin (3-O-β-d-glucopyranosyl (1→2)-β-d-glucopyranosyl (1→4)-β-d-galactopyranoside-25R, 5α-spirostane-2α,3β-diol), isolated from the leaves of Malvastrum coromandelianum in regulating thyrotoxicosis in rats" [Bioorg. Med. Chem. Lett. 26 (2016) 4804-4807]. Bioorg Med Chem Lett. 2017 May 15;27(10):2238. doi: 10.1016/j.bmcl.2017.03.048. Epub 2017 Mar 30. PubMed PMID: 28365194. 2: Panda S, Kar A. Role of a gitogenin-type steroidal saponin (3-O-β-d-glucopyranosyl (1→2)-β-d-glucopyranosyl (1→4)-β-d-galactopyranoside-25R,5α-spirostane-2α,3β-diol), isolated from the leaves of Malvastrum coromandelianum in regulating thyrotoxicosis in rats. Bioorg Med Chem Lett. 2016 Oct 1;26(19):4804-4807. doi: 10.1016/j.bmcl.2016.08.025. Epub 2016 Aug 10. Erratum in: Bioorg Med Chem Lett. 2017 May 15;27(10 ):2238. PubMed PMID: 27561715. 3: IWAMOTO HK, BELL FK, et al. Digitalis VI, pharmacodynamic studies of gitogenin. J Pharmacol Exp Ther. 1947 Oct;91(2):130-2. PubMed PMID: 20270112.