MedKoo Cat#: 128722 | Name: 84-B10
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

84-B10 is a derivative of 3-phenylglutaric acid.1 It restores mitochondrial architecture and increases spare respiratory capacity in TKPTS renal tubular epithelial cells when used at concentrations ranging from 10 to 100 µM.

Chemical Structure

84-B10
84-B10
CAS#698346-43-9

Theoretical Analysis

MedKoo Cat#: 128722

Name: 84-B10

CAS#: 698346-43-9

Chemical Formula: C25H22F3NO5

Exact Mass: 473.1450

Molecular Weight: 473.45

Elemental Analysis: C, 63.42; H, 4.68; F, 12.04; N, 2.96; O, 16.90

Price and Availability

Size Price Availability Quantity
1mg USD 350.00 2 Weeks
5mg USD 650.00 2 Weeks
10mg USD 950.00 2 Weeks
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Related CAS #
No Data
Synonym
84-B10; 84 B10; 84B10
IUPAC/Chemical Name
5-((2-(4-methoxyphenoxy)-5-(trifluoromethyl)phenyl)amino)-5-oxo-3-phenylpentanoic acid
InChi Key
UMUXAMJXLBOQNN-UHFFFAOYSA-N
InChi Code
InChI=1S/C25H22F3NO5/c1-33-19-8-10-20(11-9-19)34-22-12-7-18(25(26,27)28)15-21(22)29-23(30)13-17(14-24(31)32)16-5-3-2-4-6-16/h2-12,15,17H,13-14H2,1H3,(H,29,30)(H,31,32)
SMILES Code
O=C(CC(CC(NC1=CC(C(F)(F)F)=CC=C1OC2=CC=C(C=C2)OC)=O)C3=CC=CC=C3)O
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 473.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Fan, J., Xu, X., Li, Y., et al. A novel 3-phenylglutaric acid derivative (84-B10) alleviates cisplatin-induced acute kidney injury by inhibiting mitochondrial oxidative stress-mediated ferroptosis. Free. Radic. Biol. Med. 194, 84-98 (2023).