MedKoo Cat#: 584931 | Name: Oxamarin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Oxamarin is used in treatment of varicose veins.

Chemical Structure

Oxamarin
Oxamarin
CAS#15301-80-1 (free base)

Theoretical Analysis

MedKoo Cat#: 584931

Name: Oxamarin

CAS#: 15301-80-1 (free base)

Chemical Formula: C22H34N2O4

Exact Mass: 390.2519

Molecular Weight: 390.52

Elemental Analysis: C, 67.66; H, 8.78; N, 7.17; O, 16.39

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
6830-17-7 (HCl); 15301-80-1 (free base)
Synonym
Oxamarin; Oxamarine; Ossamarina; Oxamarin; Oxamarina
IUPAC/Chemical Name
2H-1-Benzopyran-2-one, 6,7-bis(2-(diethylamino)ethoxy)-4-methyl-
InChi Key
KDZPIXVLPYVHDO-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H34N2O4/c1-6-23(7-2)10-12-26-20-15-18-17(5)14-22(25)28-19(18)16-21(20)27-13-11-24(8-3)9-4/h14-16H,6-13H2,1-5H3
SMILES Code
O=C1C=C(C)C2=CC(OCCN(CC)CC)=C(OCCN(CC)CC)C=C2O1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 390.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Ciaceri G, Pennisi G. [Protective action of oxamarine in experimental arthropathy due to tubercullar bacilli]. Boll Chim Farm. 1972 Oct;111(10):626-30. Italian. PubMed PMID: 4630139. 2: Ciaceri G, Marini P. [Transcutaneous absorption of oxamarin (4-methyl-6,7-(bis-diethylaminoethoxy)-coumarin)]. Boll Chim Farm. 1972 May;111(5):321-7. Italian. PubMed PMID: 5050929. 3: Frandoli G, Turazza G, Spreafico PL. Comparative investigations on the treatment of the varicose syndrome with 4-methyl-6,7-(bis-beta-diethyl-aminoethoxy)-coumarine hydrochloride (oxamarine), with the disodium salt of disulphuric ester of 4-methyl-aesculetol and with tri-hydroxy-ethylrutoside (troxerutin). Panminerva Med. 1972 Sep;14(9):290-5. PubMed PMID: 4618898.