RYL-634 | MedKoo

MedKoo Cat#: 555485 | Name: RYL-634

Description:

WARNING: This product is for research use only, not for human or veterinary use.

RYL-634 is a Potent Broad-Spectrum Antiviral Inhibitor with EC50 = 5 nM. RYL-634 showed excellent broad-spectrum inhibition activity against various pathogenic viruses, including hepatitis C virus, dengue virus, Zika virus, chikungunya virus, enterovirus 71, human immunodeficiency virus, respiratory syncytial virus, and others.

Chemical Structure

RYL-634

CAS#Unknown

Theoretical Analysis

MedKoo Cat#: 555485

Name: RYL-634

CAS#: Unknown

Chemical Formula: C26H24F2N2O2

Exact Mass: 434.1806

Molecular Weight: 434.49

Elemental Analysis: C, 71.87; H, 5.57; F, 8.75; N, 6.45; O, 7.36

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

RYL-634; RYL 634; RYL634;

IUPAC/Chemical Name

2-(4-(4-(Diethylamino)phenoxy)-3-fluorophenyl)-5-fluoro-3-methylquinolin-4(1H)-one

InChi Key

LKIAZDKZPNFTIJ-UHFFFAOYSA-N

InChi Code

InChI=1S/C26H24F2N2O2/c1-4-30(5-2)18-10-12-19(13-11-18)32-23-14-9-17(15-21(23)28)25-16(3)26(31)24-20(27)7-6-8-22(24)29-25/h6-15H,4-5H2,1-3H3,(H,29,31)

SMILES Code

O=C1C(C)=C(C2=CC=C(OC3=CC=C(N(CC)CC)C=C3)C(F)=C2)NC4=C1C(F)=CC=C4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 434.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Yang Y, Cao L, Gao H, Wu Y, Wang Y, Fang F, Lan T, Lou Z, Rao Y. Discovery, Optimization, and Target Identification of Novel Potent Broad-Spectrum Antiviral Inhibitors. J Med Chem. 2019 Apr 12. doi: 10.1021/acs.jmedchem.9b00091. [Epub ahead of print] PubMed PMID: 30938999.