MedKoo Cat#: 573435 | Name: Adimolol, (R)-

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Adimolol, (R)-, is an antihypertensive.

Chemical Structure

Adimolol, (R)-
CAS#185517-22-0

Theoretical Analysis

MedKoo Cat#: 573435

Name: Adimolol, (R)-

CAS#: 185517-22-0

Chemical Formula: C25H29N3O3

Exact Mass: 419.2209

Molecular Weight: 419.53

Elemental Analysis: C, 71.57; H, 6.97; N, 10.02; O, 11.44

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Adimolol, (R)-
IUPAC/Chemical Name
2H-Benzimidazol-2-one, 1,3-dihydro-1-(3-(((2R)-2-hydroxy-3-(1-naphthalenyloxy)propyl)amino)-3-methylbutyl)-
InChi Key
YWRIUGFSIQMHJK-LJQANCHMSA-N
InChi Code
1S/C25H29N3O3/c1-25(2,14-15-28-22-12-6-5-11-21(22)27-24(28)30)26-16-19(29)17-31-23-13-7-9-18-8-3-4-10-20(18)23/h3-13,19,26,29H,14-17H2,1-2H3,(H,27,30)/t19-/m1/s1
SMILES Code
CC(C)(CCn1c2ccccc2[nH]c1=O)NC[C@H](COc3cccc4c3cccc4)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 419.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Palluk R, Hoefke W. Blood pressure lowering action and alpha-adrenolytic effect of adimolol in rats. Arch Int Pharmacodyn Ther. 1989 Sep-Oct;301:215-27. PubMed PMID: 2576194. 2: Elliott HL, Jones CR, Deighton NM, Meredith PA, Reid JL. Adimolol, a long acting beta-adrenoceptor blocker in man. Br J Clin Pharmacol. 1987 May;23(5):511-21. PubMed PMID: 2885022; PubMed Central PMCID: PMC1386186. 3: Palluk R, Hoefke W, Gaida W, Mierau J, Bechtel WD. Interactions of MEN 935 (adimolol), a long acting beta- and alpha-adrenolytic antihypertensive agent, with postsynaptic alpha-adrenoceptors in different isolated blood vessels--influence of angiotensin II. Naunyn Schmiedebergs Arch Pharmacol. 1986 Jul;333(3):277-83. PubMed PMID: 3020439.