MedKoo Cat#: 564997 | Name: ADX10059 Hydrochloride
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

ADX10059 Hydrochloride is a metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator.

Chemical Structure

ADX10059 Hydrochloride
ADX10059 Hydrochloride
CAS#757949-98-7 (HCl)

Theoretical Analysis

MedKoo Cat#: 564997

Name: ADX10059 Hydrochloride

CAS#: 757949-98-7 (HCl)

Chemical Formula: C15H14ClFN2

Exact Mass: 0.0000

Molecular Weight: 276.74

Elemental Analysis: C, 65.10; H, 5.10; Cl, 12.81; F, 6.87; N, 10.12

Price and Availability

Size Price Availability Quantity
10mg USD 450.00 2 Weeks
50mg USD 1,450.00 2 Weeks
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Synonym
ADX-10059 Hydrochloride; ADX10059 Hydrochloride; ADX 10059 Hydrochloride; ADX10059 HCl; Raseglurant HCl; Raseglurant Hydrochloride
IUPAC/Chemical Name
2-((3-Fluorophenyl)ethynyl)-4,6-dimethylpyridin-3-amine Hydrochloride
InChi Key
BDXXMGYKLQZXOU-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H13FN2.ClH/c1-10-8-11(2)18-14(15(10)17)7-6-12-4-3-5-13(16)9-12;/h3-5,8-9H,17H2,1-2H3;1H
SMILES Code
NC1=C(C)C=C(C)N=C1C#CC2=CC=CC(F)=C2.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Certificate of Analysis
Safety Data Sheet (SDS)

Preparing Stock Solutions

The following data is based on the product molecular weight 276.74 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Tomillero A, Moral MA. Gateways to clinical trials. Methods Find Exp Clin Pharmacol. 2009 Dec;31(10):661-700. PMID: 20140276.