KL-1 is an inhibitor of SEC and transcription elongation by Pol II which disrupts the cyclin T1-AFF4 interaction within SEC, and attenuates SEC-dependent rapid transcriptional responses. KL-1 inhibits MYC transcriptional programs.
MedKoo Cat#: 564992
Name: KL-1
CAS#: 900308-84-1
Chemical Formula: C18H16ClNO4
Exact Mass: 345.0768
Molecular Weight: 345.78
Elemental Analysis: C, 62.52; H, 4.66; Cl, 10.25; N, 4.05; O, 18.51
The following data is based on the product molecular weight 345.78 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
