LY 183648 | CAS#102993-90-8

MedKoo Cat#: 525486 | Name: LY 183648

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LY 183648 has antiestrogenic activity. LY117018 inhibited PAIII metastasis to the gluteal (97%) and iliac lymph nodes (88%).

Chemical Structure

LY 183648

CAS#102993-90-8

Theoretical Analysis

MedKoo Cat#: 525486

Name: LY 183648

CAS#: 102993-90-8

Chemical Formula: C20H14Cl2N4

Exact Mass: 380.0596

Molecular Weight: 381.26

Elemental Analysis: C, 63.01; H, 3.70; Cl, 18.60; N, 14.70

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

LY 183648; LY183648; LY-183648.

IUPAC/Chemical Name

Pyrimidine, 5-(bis(4-chlorophenyl)-1H-imidazol-1-ylmethyl)-

InChi Key

PWNCFCILBAAISL-UHFFFAOYSA-N

InChi Code

InChI=1S/C20H14Cl2N4/c21-18-5-1-15(2-6-18)20(26-10-9-23-14-26,17-11-24-13-25-12-17)16-3-7-19(22)8-4-16/h1-14H

SMILES Code

ClC1=CC=C(C(C2=CN=CN=C2)(C3=CC=C(Cl)C=C3)N4C=CN=C4)C=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

1: Neubauer BL, Best KL, Goode RL, Heiman ML, Hoover DM, Robertson DW, Sarosdy MF, Shaar CJ, Tanzer LR, Merriman RL. Comparative antitumor effects of hormonal ablation, estrogen agonist, estrogen cytotoxic derivative, and antiestrogen in the PAIII rat prostatic adenocarcinoma. Cancer Res. 1992 Sep 1;52(17):4663-71. PubMed PMID: 1511432.

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 381.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.