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MedKoo Cat#: 564860 | Name: pNPP

Description:

WARNING: This product is for research use only, not for human or veterinary use.

pNPP is a non-specific phosphatase substrate.

Chemical Structure

pNPP
pNPP
CAS#4264-83-9

Theoretical Analysis

MedKoo Cat#: 564860

Name: pNPP

CAS#: 4264-83-9

Chemical Formula: C6H4NNa2O6P

Exact Mass:

Molecular Weight: 263.05

Elemental Analysis: C, 27.40; H, 1.53; N, 5.32; Na, 17.48; O, 36.49; P, 11.77

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
pNPP
IUPAC/Chemical Name
p-Nitrophenyl phosphate; Sodium p-nitrophenyl phosphate; Disodium 4-Nitrophenylphosphate
InChi Key
VIYFPAMJCJLZKD-UHFFFAOYSA-L
InChi Code
InChI=1S/C6H6NO6P.2Na/c8-7(9)5-1-3-6(4-2-5)13-14(10,11)12;;/h1-4H,(H2,10,11,12);;/q;2*+1/p-2
SMILES Code
O=P([O-])([O-])OC1=CC=C([N+]([O-])=O)C=C1.[Na+].[Na+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 263.05 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Lountos GT, Cherry S, Tropea JE, Waugh DS. Structural analysis of human dual-specificity phosphatase 22 complexed with a phosphotyrosine-like substrate. Acta Crystallogr F Struct Biol Commun. 2015 Feb;71(Pt 2):199-205. doi: 10.1107/S2053230X15000217. Epub 2015 Jan 28. PubMed PMID: 25664796; PubMed Central PMCID: PMC4321476. 2: Pallen CJ, Wang JH. Calmodulin-stimulated dephosphorylation of p-nitrophenyl phosphate and free phosphotyrosine by calcineurin. J Biol Chem. 1983 Jul 25;258(14):8550-3. PubMed PMID: 6190810. 3: Granjeiro JM, Ferreira CV, Granjeiro PA, Da Silva CC, Taga EM, Volpe PL, Aoyama H. Inhibition of bovine kidney low molecular mass phosphotyrosine protein phosphatase by uric acid. J Enzyme Inhib Med Chem. 2002 Oct;17(5):345-50. PubMed PMID: 12683751.