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MedKoo Cat#: 563221 | Name: Spongosine
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Spongosine is a pivotal intercellular signal transmitter.

Chemical Structure

Spongosine
Spongosine
CAS#24723-77-1

Theoretical Analysis

MedKoo Cat#: 563221

Name: Spongosine

CAS#: 24723-77-1

Chemical Formula: C11H15N5O5

Exact Mass: 297.1073

Molecular Weight: 297.27

Elemental Analysis: C, 44.44; H, 5.09; N, 23.56; O, 26.91

Price and Availability

Size Price Availability Quantity
5mg USD 275.00 2 Weeks
25mg USD 550.00 2 Weeks
100mg USD 900.00 2 Weeks
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Related CAS #
No Data
Synonym
Spongosine; 2-Methoxy adenosine;
IUPAC/Chemical Name
(2R,3R,4S,5R)-2-(6-Amino-2-methoxypurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
InChi Key
AJACDNCVEGIBNA-KQYNXXCUSA-N
InChi Code
InChI=1S/C11H15N5O5/c1-20-11-14-8(12)5-9(15-11)16(3-13-5)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14,15)/t4-,6-,7-,10-/m1/s1
SMILES Code
O[C@H]1[C@H](N2C=NC3=C(N)N=C(OC)N=C23)O[C@H](CO)[C@H]1O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.03.00
More Info
Product Data
Product Data
Instruction
View handling instruction
Biological target:
Spongosine is a purine nucleoside analog.
In vitro activity:
To be determined
In vivo activity:
To be determined

Preparing Stock Solutions

The following data is based on the product molecular weight 297.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
To be determined
In vitro protocol:
To be determined
In vivo protocol:
To be determined
1: Bertin MJ, Schwartz SL, Lee J, Korobeynikov A, Dorrestein PC, Gerwick L, Gerwick WH. Spongosine production by a Vibrio harveyi strain associated with the sponge Tectitethya crypta. J Nat Prod. 2015 Mar 27;78(3):493-9. doi: 10.1021/np5009762. Epub 2015 Feb 10. PubMed PMID: 25668560; PubMed Central PMCID: PMC5065018. 2: Ebada SS, Proksch P. Chemical and pharmacological significance of natural guanidines from marine invertebrates. Mini Rev Med Chem. 2011 Mar;11(3):225-46. Review. PubMed PMID: 21534931.