AY 31906 | CAS# 124788-46-1 | Diuretic

MedKoo Cat#: 573358 | Name: AY 31906

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AY 31906 is a high ceiling diuretic with a relative potassium-sparing effect. AY 31906 has been shown to produce significant increases in the fractional excretion of sodium and chloride in dogs at a dose that produces no statistically significant changes in the fractional excretion of potassium, glomerular filtration rate or renal plasma flow.

Chemical Structure

AY 31906

CAS#124788-46-1

Theoretical Analysis

MedKoo Cat#: 573358

Name: AY 31906

CAS#: 124788-46-1

Chemical Formula: C15H24N6O3S

Exact Mass: 368.1631

Molecular Weight: 368.46

Elemental Analysis: C, 48.90; H, 6.57; N, 22.81; O, 13.03; S, 8.70

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

AY 31906, AY-31,906

IUPAC/Chemical Name

5-Pyrimidinesulfonamide, 2-amino-4-(bicyclo(2.2.1)hept-2-ylamino)-N-(((1-methylethyl)amino)carbonyl)-, exo-

InChi Key

ZJGXCMUCLPBLHI-UHFFFAOYSA-N

InChi Code

1S/C15H24N6O3S/c1-8(2)18-15(22)21-25(23,24)12-7-17-14(16)20-13(12)19-11-6-9-3-4-10(11)5-9/h7-11H,3-6H2,1-2H3,(H2,18,21,22)(H3,16,17,19,20)

SMILES Code

c1(nc(c(cn1)S(=O)(=O)NC(=O)NC(C)C)N[C@@H]1[C@@H]2CC[C@@H](C1)C2)N

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 368.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Ackerman DM, Brady MM, MacLean AG, Smith TM. AY-31,906, a novel high ceiling diuretic: characterization of its relative potassium-sparing actions in rats and dogs. J Pharmacol Exp Ther. 1989 Dec;251(3):1113-9. PubMed PMID: 2600806.