T63 | Osteoclast Differentiation Inhibitor

MedKoo Cat#: 564771 | Name: T63

Description:

WARNING: This product is for research use only, not for human or veterinary use.

T63 is an inhibitor of osteoclast differentiation through regulating MAPKs and Akt signaling pathways.

Chemical Structure

T63

CAS#NONE

Theoretical Analysis

MedKoo Cat#: 564771

Name: T63

CAS#: NONE

Chemical Formula: C12H14N2O2S

Exact Mass: 250.0776

Molecular Weight: 250.32

Elemental Analysis: C, 57.58; H, 5.64; N, 11.19; O, 12.78; S, 12.81

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

T-63; T 63; T63

IUPAC/Chemical Name

N-(Cyclopropylmethyl)-5-(thiophen-2-yl)-4,5-dihydroisoxazole-3-carboxamide

InChi Key

CMPHBHQOQYAKSF-UHFFFAOYSA-N

InChi Code

InChI=1S/C12H14N2O2S/c15-12(13-7-8-3-4-8)9-6-10(16-14-9)11-2-1-5-17-11/h1-2,5,8,10H,3-4,6-7H2,(H,13,15)

SMILES Code

O=C(C1=NOC(C2=CC=CS2)C1)NCC3CC3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 250.32 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Zhao XL, Chen JJ, Si SY, Chen LF, Wang Z. T63 inhibits osteoclast differentiation through regulating MAPKs and Akt signaling pathways. Eur J Pharmacol. 2018 Sep 5;834:30-35. doi: 10.1016/j.ejphar.2018.07.009. Epub 2018 Jul 19. PubMed PMID: 30012501.