MedKoo Cat#: 573290 | Name: Asocainol hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Asocainol hydrochloride ia an antiarrhythmic drug which inhibits slow Ca2+ influx. This is accompanied by alterations in normal Na+-carried action potentials. Therefore, Asocainol not only inhibits Ca2+ inflow but also interferes with the fast inward Na+ current.

Chemical Structure

Asocainol hydrochloride
Asocainol hydrochloride
CAS#91574-89-9

Theoretical Analysis

MedKoo Cat#: 573290

Name: Asocainol hydrochloride

CAS#: 91574-89-9

Chemical Formula: C27H32ClNO3

Exact Mass: 453.2071

Molecular Weight: 454.01

Elemental Analysis: C, 71.43; H, 7.10; Cl, 7.81; N, 3.09; O, 10.57

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Asocainol HCl, Asocainol hydrochloride, Go 4704A
IUPAC/Chemical Name
5H-Dibenz(d,f)azonin-1-ol, 6,7,8,9-tetrahydro-2,12-dimethoxy-7-methyl-6-(2-phenylethyl)-, hydrochloride, (+-)-
InChi Key
JTGDTQLVMHZOHX-UHFFFAOYSA-N
InChi Code
1S/C27H31NO3.ClH/c1-28-16-15-20-10-13-23(30-2)18-24(20)26-21(11-14-25(31-3)27(26)29)17-22(28)12-9-19-7-5-4-6-8-19;/h4-8,10-11,13-14,18,22,29H,9,12,15-17H2,1-3H3;1H
SMILES Code
C1c2ccc(OC)c(O)c2c2c(ccc(c2)OC)CC[N@@]([C@@H]1CCc1ccccc1)C.Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 454.01 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Gödicke J, Herzig S, Mescheder A, Mohr K, Steinke F. Enantioselectivity of asocainol studied at different conditions: a novel approach to check the feasibility of molecular models of antiarrhythmic drug action. Naunyn Schmiedebergs Arch Pharmacol. 1992 Sep;346(3):345-51. PubMed PMID: 1328897. 2: Späh F. Asocainol, a new antiarrhythmic drug with natrium- and calcium-antagonistic effects on ventricular myocardium. J Cardiovasc Pharmacol. 1984 Nov-Dec;6(6):1027-35. PubMed PMID: 6084758. 3: Langenfeld H, Haverkampf K, Antoni H. Electrophysiological profile of the antiarrhythmic compound asocainol studied on perfused guinea-pig hearts and on isolated cardiac preparations. Naunyn Schmiedebergs Arch Pharmacol. 1984 Jun;326(2):155-62. PubMed PMID: 6472493.