MedKoo Cat#: 145918 | Name: ASP-9831

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ASP-9831 is a small molecule being researched for its potential in treating various cancers, particularly by targeting specific enzymes involved in tumor progression. It works by inhibiting certain proteases that are critical for the growth and metastasis of cancer cells. The mechanism of ASP-9831 involves blocking the activity of these enzymes, which disrupts cancer cell survival and promotes cell death. Due to its targeted action, ASP-9831 is being studied as a potential therapeutic agent for oncology, with a focus on improving cancer treatment outcomes.

Chemical Structure

ASP-9831
ASP-9831
CAS#728013-50-1

Theoretical Analysis

MedKoo Cat#: 145918

Name: ASP-9831

CAS#: 728013-50-1

Chemical Formula: C20H23N3O3

Exact Mass: 353.1700

Molecular Weight: 353.42

Elemental Analysis: C, 67.97; H, 6.56; N, 11.89; O, 13.58

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
ASP-9831; ASP9831; ASP 9831;
IUPAC/Chemical Name
3-(7-ethyl-2-(methoxymethyl)-4-(5-methylpyridin-3-yl)pyrrolo[1,2-b]pyridazin-3-yl)propanoic acid
InChi Key
UECHVFIKTBUKTP-UHFFFAOYSA-N
InChi Code
1S/C20H23N3O3/c1-4-15-5-7-18-20(14-9-13(2)10-21-11-14)16(6-8-19(24)25)17(12-26-3)22-23(15)18/h5,7,9-11H,4,6,8,12H2,1-3H3,(H,24,25)
SMILES Code
CCC1=CC=C2N1N=C(COC)C(CCC(O)=O)=C2C3=CN=CC(C)=C3
Appearance
To be determined
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 353.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Ratziu V, Bedossa P, Francque SM, Larrey D, Aithal GP, Serfaty L, Voiculescu M, Preotescu L, Nevens F, De Lédinghen V, Kirchner GI, Trunecka P, Ryder SD, Day CP, Takeda J, Traudtner K. Lack of efficacy of an inhibitor of PDE4 in phase 1 and 2 trials of patients with nonalcoholic steatohepatitis. Clin Gastroenterol Hepatol. 2014 Oct;12(10):1724-30.e5. doi: 10.1016/j.cgh.2014.01.040. Epub 2014 Feb 12. PMID: 24530600.