Argtide | CAS# 138111-66-7 | LHRH antagonist

MedKoo Cat#: 573268 | Name: Argtide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Argtide is an luteinizing hormone releasing hormone (LHRH) antagonist.

Chemical Structure

Argtide

CAS#138111-66-7

Theoretical Analysis

MedKoo Cat#: 573268

Name: Argtide

CAS#: 138111-66-7

Chemical Formula: C80H104ClN21O14

Exact Mass: 1617.7760

Molecular Weight: 1619.29

Elemental Analysis: C, 59.34; H, 6.47; Cl, 2.19; N, 18.17; O, 13.83

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Argtide

IUPAC/Chemical Name

N-Acetyl-3-(3-quinolyl)alanyl-3-(4-chlorophenyl)alanyl-3-(3-pyridyl)alanyl-seryl-3-(4-pyrazinylcarbonylaminocyclohexyl)alanyl-N(epsilon)-picolinoyllysyl-leucyl-arginyl-prolyl-alaninamide

InChi Key

RMGMPGFOSVZOOU-IGLMWVOESA-N

InChi Code

1S/C80H104ClN21O14/c1-46(2)36-63(98-68(106)55(82)16-7-9-31-92-70(108)60-18-8-10-30-90-60)71(109)97-61(19-12-32-93-79(86)87)75(113)100-35-13-20-66(100)77(115)102(74(112)58(85)39-48-21-25-53(81)26-22-48)80(4,67(105)62(95-47(3)104)41-51-37-52-15-5-6-17-59(52)94-43-51)78(116)101(76(114)65(45-103)99-69(107)56(83)40-50-14-11-29-88-42-50)73(111)57(84)38-49-23-27-54(28-24-49)96-72(110)64-44-89-33-34-91-64/h5-6,8,10-11,14-15,17-18,21-22,25-26,29-30,33-34,37,42-44,46,49,54-58,61-63,65-66,103H,7,9,12-13,16,19-20,23-24,27-28,31-32,35-36,38-41,45,82-85H2,1-4H3,(H,92,108)(H,95,104)(H,96,110)(H,97,109)(H,98,106)(H,99,107)(H4,86,87,93)/t49-,54+,55-,56-,57+,58-,61+,62-,63+,65+,66+,80+/m1/s1

SMILES Code

C([C@](N(C([C@H]1N(CCC1)C([C@@H](NC([C@@H](NC([C@H](N)CCCCNC(=O)c1ccccn1)=O)CC(C)C)=O)CCCNC(=N)N)=O)=O)C([C@H](N)Cc1ccc(cc1)Cl)=O)(C)C([C@H](NC(=O)C)Cc1cnc2ccccc2c1)=O)(=O)N(C([C@@H](N)C[C@H]1CC[C@H](CC1)NC(=O)c1cnccn1)=O)C([C@@H](NC([C@H](N)Cc1cnccc1)=O)CO)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 1,619.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Janecka A, Ljungqvist A, Bowers C, Folkers K. Superiority of an antagonist of the luteinizing hormone releasing hormone with emphasis on arginine in position 8, named Argtide. Biochem Biophys Res Commun. 1991 Oct 15;180(1):374-9. PubMed PMID: 1656974.