ARL-17477 dihydrochloride is a selective neuronal nitrogen oxide synthase (nNOS) inhibitor that reduces ischemic cell damage after middle cerebral artery (MCA) occlusion in rats. This product displays a synergistic neuroprotective effect when combined with either an NMDA or AMPA receptor antagonist.
MedKoo Cat#: 574496
Name: ARL-17477 dihydrochloride
CAS#: 866914-87-6
Chemical Formula: C20H21Cl3N2OS
Exact Mass: 442.0440
Molecular Weight: 443.81
Elemental Analysis: C, 54.13; H, 4.77; Cl, 23.96; N, 6.31; O, 3.60; S, 7.22
The following data is based on the product molecular weight 443.81 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
