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MedKoo Cat#: 573259 | Name: Heptaminol hydrochloride
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Heptaminol hydrochloride is an amino alcohol used as a myocardial stimulant, vasodilator, and to relieve bronchospasm. Its most common therapeutic use is in orthostatic hypotension. The mechanism of heptaminol's therapeutic actions is not well understood although it has been suggested to affect catecholamine release or calcium metabolism.

Chemical Structure

Heptaminol hydrochloride
Heptaminol hydrochloride
CAS#543-15-7 (HCl)

Theoretical Analysis

MedKoo Cat#: 573259

Name: Heptaminol hydrochloride

CAS#: 543-15-7 (HCl)

Chemical Formula: C8H20ClNO

Exact Mass: 181.1233

Molecular Weight: 181.70

Elemental Analysis: C, 52.88; H, 11.09; Cl, 19.51; N, 7.71; O, 8.80

Price and Availability

Size Price Availability Quantity
100mg USD 285.00 2 Weeks
250mg USD 500.00 2 Weeks
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Related CAS #
372-66-7 (free base) 543-15-7 (HCl)
Synonym
Arcor tropfen, Cardiosintol, Corasor, Coreptil, Cortensor, Delmiton, EA-85, Heptaminol HCl, Heptaminol hydrochloride, Respirin
IUPAC/Chemical Name
2-Heptanol, 6-amino-2-methyl-, hydrochloride
InChi Key
JZNBMCOSOXIZJB-UHFFFAOYSA-N
InChi Code
1S/C8H19NO.ClH/c1-7(9)5-4-6-8(2,3)10;/h7,10H,4-6,9H2,1-3H3;1H
SMILES Code
Cl.CC(N)CCCC(C)(C)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Solvent mg/mL mM
Solubility
Soluble in DMSO 0.0 100.00
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 181.70 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Drugs for hypotension: disproportionate harms with etilefrine and heptaminol. . Prescrire Int. 2015 Jul;24(162):184. PubMed PMID: 26240886. 2: Bahloul M, Chaari A, Ben Mbarek MN, Kallel H, Bouaziz M. Use of heptaminol hydrochloride for catecholamine weaning in septic shock. Am J Ther. 2012 Jan;19(1):e8-17. doi: 10.1097/MJT.0b013e3181e9b630. PubMed PMID: 20720484. 3: GARRETT J. [Pharmacodynamic study of 6-amino-2-methyl-2-heptanol hydrochloride (heptaminol hydrochloride or R. P. 2831). I. Action of heptaminol hydrochloride on the cardiovascular and central nervous systems]. Arch Int Pharmacodyn Ther. 1954 Nov 1;100(1):17-34. French. PubMed PMID: 14350831.