Derazantinib is a multi-kinase inhibitor with pan-FGFR activity which has shown preliminary therapeutic activity against FGFR2 fusion-positive intrahepatic cholangiocarcinoma (iCCA). Derazantinib dihydrochloride is a salt of Derazantinib.
MedKoo Cat#: 573243
Name: Derazantinib dihydrochloride
CAS#: 1821329-75-2 (dihydrochloride)
Chemical Formula: C29H31Cl2FN4O
Exact Mass: 540.1859
Molecular Weight: 541.49
Elemental Analysis: C, 64.33; H, 5.77; Cl, 13.09; F, 3.51; N, 10.35; O, 2.95
The following data is based on the product molecular weight 541.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
