MedKoo Cat#: 530749 | Name: Lysine 4-nitroanilide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lysine 4-nitroanilide is a bioactive chemical.

Chemical Structure

Lysine 4-nitroanilide
Lysine 4-nitroanilide
CAS#6184-11-8

Theoretical Analysis

MedKoo Cat#: 530749

Name: Lysine 4-nitroanilide

CAS#: 6184-11-8

Chemical Formula: C12H18N4O3

Exact Mass: 266.1379

Molecular Weight: 266.30

Elemental Analysis: C, 54.12; H, 6.81; N, 21.04; O, 18.02

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Lysine 4-nitroanilide
IUPAC/Chemical Name
Hexanamide, 2,6-diamino-N-(4-nitrophenyl)-
InChi Key
VUUNELJIFNFWJC-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H18N4O3/c13-8-2-1-3-11(14)12(17)15-9-4-6-10(7-5-9)16(18)19/h4-7,11H,1-3,8,13-14H2,(H,15,17)
SMILES Code
O=C(NC1=CC=C([N+]([O-])=O)C=C1)C(N)CCCCN
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 266.30 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sousa MO, Miranda TL, Maia CN, Bittar ER, Santoro MM, Figueiredo AF. Kinetic peculiarities of human tissue kallikrein: 1--substrate activation in the catalyzed hydrolysis of H-D-valyl-L-leucyl-L-arginine 4-nitroanilide and H-D-valyl-L-leucyl-L-lysine 4-nitroanilide; 2--substrate inhibition in the catalyzed hydrolysis of N alpha-p-tosyl-L-arginine methyl ester. Arch Biochem Biophys. 2002 Apr 1;400(1):7-14. PubMed PMID: 11913965. 2: Stepanov VM, Terent'eva EYu, Voyushina TL, Gololobov MYu. Subtilisin and alpha-chymotrypsin catalyzed synthesis of peptides containing arginine and lysine p-nitroanilides as C-terminal moieties. Bioorg Med Chem. 1995 May;3(5):479-85. PubMed PMID: 7648197. 3: Blanc B, Laloi P, Atlan D, Gilbert C, Portalier R. Two cell-wall-associated aminopeptidases from Lactobacillus helveticus and the purification and characterization of APII from strain ITGL1. J Gen Microbiol. 1993 Jul;139(7):1441-8. PubMed PMID: 8371107. 4: Arbesú MJ, Valle E, Suárez-Rendueles P. Purification and characterization of aminopeptidase yspI from Schizosaccharomyces pombe. Yeast. 1993 Jun;9(6):637-44. PubMed PMID: 8346680. 5: Cowman RA, Baron SS. Studies on the subcellular localization of protease and arylaminopeptidase activities in Streptococcus sanguis ATCC 10556. J Dent Res. 1991 Dec;70(12):1508-15. PubMed PMID: 1774382. 6: Petersen LC, Brender J, Suenson E. Zymogen-activation kinetics. Modulatory effects of trans-4-(aminomethyl)cyclohexane-1-carboxylic acid and poly-D-lysine on plasminogen activation. Biochem J. 1985 Jan 1;225(1):149-58. PubMed PMID: 2579638; PubMed Central PMCID: PMC1144563. 7: Petersen LC, Clemmensen I. Kinetics of plasmin inhibition in the presence of a synthetic tripeptide substrate. The reaction with pancreatic trypsin inhibitor and two forms of alpha 2-plasmin inhibitor. Biochem J. 1981 Oct 1;199(1):121-7. PubMed PMID: 6175313; PubMed Central PMCID: PMC1163341. 8: Eggimann B, Bachmann M. Purification and Partial Characterization of an Aminopeptidase from Lactobacillus lactis. Appl Environ Microbiol. 1980 Nov;40(5):876-82. PubMed PMID: 16345655; PubMed Central PMCID: PMC291682. 9: Papke G, Blobel H. [Qualitative and quantitative determinations of staphylokinase-activity (author's transl)]. Zentralbl Bakteriol Orig A. 1978 Dec;242(4):456-61. German. PubMed PMID: 219637. 10: Bury AF, Coolbear T, Savery CR. Separation and properties of two arylamidases from rat cardiac-muscle extracts. Biochem J. 1977 Jun 1;163(3):565-70. PubMed PMID: 406901; PubMed Central PMCID: PMC1164737.