MedKoo Cat#: 341213 | Name: Yohimbic acid

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Yohimbic acid is a biochemical.

Chemical Structure

Yohimbic acid
Yohimbic acid
CAS#522-87-2

Theoretical Analysis

MedKoo Cat#: 341213

Name: Yohimbic acid

CAS#: 522-87-2

Chemical Formula: C20H24N2O3

Exact Mass: 340.1787

Molecular Weight: 340.42

Elemental Analysis: C, 70.57; H, 7.11; N, 8.23; O, 14.10

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Yohimbic acid; NSC-95096; NSC 95096; NSC95096.
IUPAC/Chemical Name
17alpha-Hydroxyyohimban-16alpha-carboxylic acid
InChi Key
AADVZSXPNRLYLV-GKMXPDSGSA-N
InChi Code
InChI=1S/C20H24N2O3/c23-17-6-5-11-10-22-8-7-13-12-3-1-2-4-15(12)21-19(13)16(22)9-14(11)18(17)20(24)25/h1-4,11,14,16-18,21,23H,5-10H2,(H,24,25)/t11-,14-,16-,17-,18+/m0/s1
SMILES Code
[H][C@]12C(NC3=C4C=CC=C3)=C4CCN1C[C@@]5(CC[C@H](O)[C@H](C(O)=O)[C@]5(C2)[H])[H]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 340.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Lucas D, Neal-Kababick J, Zweigenbaum J. Characterization and quantitation of yohimbine and its analogs in botanicals and dietary supplements using LC/QTOF-MS and LC/QQQ-MS for determination of the presence of bark extract and yohimbine adulteration. J AOAC Int. 2015 Mar-Apr;98(2):330-5. doi: 10.5740/jaoacint.14-246. PubMed PMID: 25905738. 2: RAYMOND-HAMET. [ON THE SUCCESSIVE STAGES OF THE SYMPATHICOLYTIC ACTIVITY OF YOHIMBIC ACID]. C R Hebd Seances Acad Sci. 1963 Oct 14;257:2351-4. French. PubMed PMID: 14093965. 3: ARRIGO A, COSI V, SAVOLDI F. [EEG study of the central action of yohimbine and yohimbic acid. (Experimental research)]. Boll Soc Ital Biol Sper. 1961 Aug 31;37:787-90. Italian. PubMed PMID: 13862577. 4: RAYMOND HAMET. [Demonstration of the direct vasodilatory action of yohimbic acid and Py-tetrahydroquinoline]. C R Hebd Seances Acad Sci. 1960 Jun 27;250:4473-5. French. PubMed PMID: 13854468. 5: KLUPP H. [Pharmacological studies on yohimbic acid ethyl ester (A 38) and 4-=2-(p-butoxyphenyl)-1,3-dioxolan-2-ylmethyl=-morpholine methobromide (Q 160) as well as the influence of these substances on reserpine action]. Arzneimittelforschung. 1955 Aug;5(8):432-6. German. PubMed PMID: 13276244. 6: RAYMOND-HAMET. [Sympatholytic activity and toxicity of an amphoteric demethylated derivative of yohimbine: yohimbic acid]. C R Hebd Seances Acad Sci. 1951 Oct 29;233(18):1069-71. Undetermined Language. PubMed PMID: 14896545.