AVE6971 HCl | CAS# | Antistaphyloccocal Agent

MedKoo Cat#: 564679 | Name: AVE6971 HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AVE6971 is an antibacterial agent and antistaphyloccocal agent which attenuates inhibition of hERG potassium channel current.

Chemical Structure

AVE6971 HCl

CAS#AVE6971 HCl

Theoretical Analysis

MedKoo Cat#: 564679

Name: AVE6971 HCl

CAS#: AVE6971 HCl

Chemical Formula: C25H30N2O4S2

Exact Mass: 486.1647

Molecular Weight: 486.65

Elemental Analysis: C, 61.70; H, 6.21; N, 5.76; O, 13.15; S, 13.18

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

AVE6971 HCl 710944-85-7 (free base)

Synonym

AVE-6971; AVE 6971; AVE6971; AVE6971 HCl;

IUPAC/Chemical Name

(3R,4R)-4-((S)-3-Hydroxy-3-(6-methoxyquinolin-4-yl)propyl)-1-(2-(thiophen-2-ylthio)ethyl)piperidine-3-carboxylic acid

InChi Key

DSLCRNMTGWECHB-FHZYATBESA-N

InChi Code

InChI=1S/C25H30N2O4S2/c1-31-18-5-6-22-20(15-18)19(8-10-26-22)23(28)7-4-17-9-11-27(16-21(17)25(29)30)12-14-33-24-3-2-13-32-24/h2-3,5-6,8,10,13,15,17,21,23,28H,4,7,9,11-12,14,16H2,1H3,(H,29,30)/t17-,21+,23+/m1/s1

SMILES Code

O=C([C@H]1CN(CCSC2=CC=CS2)CC[C@H]1CC[C@H](O)C3=CC=NC4=CC=C(OC)C=C34)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>3 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 486.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Wiles JA, Phadke AS, Bradbury BJ, Pucci MJ, Thanassi JA, Deshpande M. Selenophene-containing inhibitors of type IIA bacterial topoisomerases. J Med Chem. 2011 May 12;54(9):3418-25. doi: 10.1021/jm2002124. Epub 2011 Apr 13. PubMed PMID: 21443219. 2: Salvador A, Gautier JY, Pasquier O, Merdjan H. Liquid chromatography-tandem mass spectrometric determination of a new antibacterial agent (AVE6971) in human white blood cells. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Aug 15;855(2):173-9. Epub 2007 May 10. PubMed PMID: 17540623.