MedKoo Cat#: 591485 | Name: Pridefine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pridefine (AHR-1,118) is a drug which was investigated as an antidepressant in the late 1970s and early 1980s, but was never marketed. It acts as a balanced reuptake inhibitor of serotonin, dopamine, and norepinephrine, and also has some weak releasing activity.

Chemical Structure

Pridefine
CAS#5370-41-2

Theoretical Analysis

MedKoo Cat#: 591485

Name: Pridefine

CAS#: 5370-41-2

Chemical Formula: C19H21N

Exact Mass: 263.1674

Molecular Weight: 263.38

Elemental Analysis: C, 86.64; H, 8.04; N, 5.32

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Pridefine; Pridefina;
IUPAC/Chemical Name
Pyrrolidine, 3-(diphenylmethylene)-1-ethyl-
InChi Key
BJUHVJHOJBHLJS-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H21N/c1-2-20-14-13-18(15-20)19(16-9-5-3-6-10-16)17-11-7-4-8-12-17/h3-12H,2,13-15H2,1H3
SMILES Code
CCN1C/C(CC1)=C(C2=CC=CC=C2)/C3=CC=CC=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 263.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Simpson GM, White KL, Boyd JL, Cooper TB, Halaris A, Wilson IC, Raman EJ, Ruther E. Relationship between plasma antidepressant levels and clinical outcome for inpatients receiving imipramine. Am J Psychiatry. 1982 Mar;139(3):358-60. PubMed PMID: 7036761. 2: DeMet EM, Vosmer G, Halaris AE. Noncompetitive amine uptake inhibition by the new antidepressant pridefine. J Neurochem. 1981 Mar;36(3):917-23. PubMed PMID: 7205281. 3: Vosmer G, DeMet EM, Halaris AE. Action of the antidepressant pridefine (AHR-1118) on biogenic amines in the rat brain. Biochem Pharmacol. 1980 Oct 1;29(19):2557-62. PubMed PMID: 7426062. 4: Halaris AE, Demet EM. Open trial evaluation of a pyrrolidine derivative (AHR-1118) on norepinephrine metabolism. Prog Neuropsychopharmacol. 1980;4(1):43-9. PubMed PMID: 7406986.